Does the Prefrontal Cortex Play an Essential Role in Consciousness? Insights from Intracranial Electrical Stimulation of the Human Brain DOI Creative Commons
Omri Raccah, Ned Block, Kieran C. R. Fox

et al.

Journal of Neuroscience, Journal Year: 2021, Volume and Issue: 41(10), P. 2076 - 2087

Published: March 10, 2021

A central debate in philosophy and neuroscience pertains to whether PFC activity plays an essential role the neural basis of consciousness. Neuroimaging electrophysiology studies have revealed that contents conscious perceptual experience can be successfully decoded from activity, but these findings might confounded by postperceptual cognitive processes, such as thinking, reasoning, decision-making, are not necessary for To clarify involvement consciousness, we present a synthesis research has used intracranial electrical stimulation (iES) causal modulation human PFC. This provides compelling evidence iES only certain prefrontal regions (i.e., orbitofrontal cortex anterior cingulate cortex) reliably perturbs experience. Conversely, anterolateral sites, often considered crucial higher-order global workspace theories seldom elicits any reportable alterations Furthermore, wide variety iES-elicited effects (e.g., emotions, thoughts, olfactory visual hallucinations) exhibits no clear relation immediate environment. Therefore, there is kinds ongoing would predicted or theories. Nevertheless, cortices suggest specific subregions supporting emotional aspects Overall, this presents challenge theories, which commonly point perception based on correlative possibly information.

Language: Английский

Multiple large-scale neural networks underlying emotion regulation DOI
Carmen Morawetz,

Michael C. Riedel,

Taylor Salo

et al.

Neuroscience & Biobehavioral Reviews, Journal Year: 2020, Volume and Issue: 116, P. 382 - 395

Published: July 11, 2020

Language: Английский

Citations

163
Prefrontal excitatory/inhibitory balance in stress and emotional disorders: Evidence for over-inhibition DOI
Chloe E. Page, Laurence Coutellier

Neuroscience & Biobehavioral Reviews, Journal Year: 2019, Volume and Issue: 105, P. 39 - 51

Published: Aug. 1, 2019

Language: Английский

Citations

160
Understanding emotions DOI
Cathrine V. Jansson‐Boyd, Peter Bright

Elsevier eBooks, Journal Year: 2024, Volume and Issue: unknown, P. 141 - 164

Published: Jan. 1, 2024

Language: Английский

Citations

157
The mouse prefrontal cortex: Unity in diversity DOI Creative Commons
Pierre Le Merre, Sofie Ährlund‐Richter, Marie Carlén

et al.

Neuron, Journal Year: 2021, Volume and Issue: 109(12), P. 1925 - 1944

Published: April 23, 2021

Language: Английский

Citations

149
Amygdala-prefrontal connectivity during emotion regulation: A meta-analysis of psychophysiological interactions DOI Creative Commons
Stella Berboth, Carmen Morawetz

Neuropsychologia, Journal Year: 2021, Volume and Issue: 153, P. 107767 - 107767

Published: Jan. 29, 2021

Given the importance of emotion regulation as a transdiagnostic factor in development psychopathology, myriad neuroimaging studies has investigated its neural underpinnings. However, single usually provide limited insight into function specific brain regions. Hence, to better understand interaction between key regions involved generation and regulation, we performed coordinate-based meta-analysis on functional magnetic resonance imaging (fMRI) that examined regulation-modulated connectivity amygdala using psychophysiological (PPI) analysis. We analyzed fifteen PPI activation likelihood estimation (ALE) algorithm. Investigating independent strategy goal revealed convergent left ventrolateral prefrontal cortex (vlPFC), which was primarily driven by implementing reappraisal strategy. A more focused analysis testing for effective coupling during down-regulation emotions specifically right dorsolateral (dlPFC), dorsomedial (dmPFC). These have been implicated regulatory processes such working memory language attribution mental states Our findings suggest not only dynamic modulation generative systems cognitive control emotions, but also highlight robustness task-modulated prefrontal-amygdala coupling, thereby informing neurally-derived models regulation.

Language: Английский

Citations

145
Polygonatum sibiricum polysaccharide prevents depression-like behaviors by reducing oxidative stress, inflammation, and cellular and synaptic damage DOI

Fengming Shen,

Zhujin Song,

Pan Xie

et al.

Journal of Ethnopharmacology, Journal Year: 2021, Volume and Issue: 275, P. 114164 - 114164

Published: April 28, 2021

Language: Английский

Citations

124
Emotional Contagion: A Brief Overview and Future Directions DOI Creative Commons
Carolina Herrando, Efthymios Constantinides

Frontiers in Psychology, Journal Year: 2021, Volume and Issue: 12

Published: July 16, 2021

Social interactions can trigger emotional contagion between individuals resulting in behavioral synchrony. Emotional be a very effective and attractive strategy communication advertising, understanding the mechanisms underlying help marketers to improve their commercial approaches or develop better ones. The purpose of this study is review classify various methodologies theoretical on contagion, identify best practices domain, ways gaging measuring contagion. based mini literature review. We different described literature. triggered by facial expressions, indirect human interactions, and/or observing other people's behavior direct interactions. Furthermore, physiologically neurologically synchronizing with state others during Regarding assessment measurement we argue that methods neuroscience tools are much more accurate than traditional research approaches. identifies guidelines for through especially interesting academia marketing practitioners. findings important field interested developing new individualized strategies general. In addition, become basis further refines compares efficacy techniques involved.

Language: Английский

Citations

124
The knowns and unknowns of boredom: a review of the literature DOI
Quentin Raffaelli, Caitlin Mills, Kalina Christoff

et al.

Experimental Brain Research, Journal Year: 2017, Volume and Issue: 236(9), P. 2451 - 2462

Published: March 28, 2017

Language: Английский

Citations

130
The impact of affective information on working memory: A pair of meta-analytic reviews of behavioral and neuroimaging evidence. DOI Creative Commons
Susanne Schweizer, Ajay B. Satpute, Shir Atzil

et al.

Psychological Bulletin, Journal Year: 2019, Volume and Issue: 145(6), P. 566 - 609

Published: April 25, 2019

Everyday life is defined by goal states that are continuously reprioritized based on available, often affective information. To pursue these goals, individuals need to process and maintain goal-relevant information, while ignoring potentially salient information distracts resources from goals. Empirically, this ability has typically been operationalized as working memory (WM) capacity. A growing body of research investigating the impact information’s salience WM In present review we address question exploring potential differential compared with neutral WM, underlying neural substrates. One-hundred 65 studies (N = 7,433) were included in meta-analysis. Results showed negligible small (d̂ −.07–.20) effects behavioral measures healthy (n 4,936) varied a function valence task-relevance. Heterogeneity analyses significant, demonstrating identify further study-specific factors individual differences moderate WM. At level (33 studies; n 683), processing versus material during tasks was associated more frequent recruitment vlPFC, amygdala, temporo-occipital cortex. contrast individuals, across those suffering mental health problems 2,041) impaired accuracy −0.21) presence material. These findings highlight importance integrating levels analysis. Finally, suggest capacity may be transdiagnostic mechanism poor health.

Language: Английский

Citations

124
Emotion Regulation of Hippocampus Using Real-Time fMRI Neurofeedback in Healthy Human DOI Creative Commons

Yashuo Zhu,

Hui Gao, Li Tong

et al.

Frontiers in Human Neuroscience, Journal Year: 2019, Volume and Issue: 13

Published: July 16, 2019

Real-time functional magnetic resonance imaging neurofeedback (rtfMRI-NF) is a prospective tool to enhance the emotion regulation capability of participants and alleviate their emotional disorders. The hippocampus key brain region in network plays significant role social cognition processing brain. However, few studies have focused on NF hippocampus. This study investigated feasibility training healthy self-regulate activation assessed effect rtfMRI-NF before after training. Twenty-six right-handed volunteers were randomly assigned experimental group receiving hippocampal (n = 13) control (CG) from intraparietal sulcus completed total four runs. defined based Montreal Neurological Institute (MNI) standard template, signal was measured as percent change relative baseline obtained by averaging fMRI for preceding 20 s long rest block. (percent change) updated every 2 displayed screen. amplitude low-frequency fluctuation regional homogeneity values calculated evaluate effects spontaneous neural activity resting-state fMRI. A general linear model (GLM) analysis separately conducted each run. Results showed that increased experiment higher than CG. They also elevated greater amygdala-hippocampus connectivity. anterior temporal lobe, parahippocampal gyrus, hippocampus, amygdala regions associated with activated during We presented proof-of-concept using up-regulation recall positive autobiographical memories. current may provide new method regulate our emotions can potentially be applied clinical treatment

Language: Английский

Citations

101