Bovine Colostrum in Pediatric Nutrition and Health DOI Open Access

Ahmet Alperen Canbolat,

Mauro Lombardo, Alicia del Carmen Mondragón

et al.

Nutrients, Journal Year: 2024, Volume and Issue: 16(24), P. 4305 - 4305

Published: Dec. 13, 2024

Bovine colostrum (BC), the first milk secreted by mammals after birth, is a trending alternative source for supplementing infants and children, offering benefits gut immune health. Its rich components, such as proteins, immunoglobulins, lactoferrin, glycans, are used to fortify diets support development. Preterm development crucial, especially in maturation of essential systems, from 2010 2020, approximately 15% all premature births occurred at less than 32 weeks gestation worldwide. This review explores composition, benefits, effects BC on general along with preterm who require special care, highlights its role growth also associated specific pediatric diseases, including necrotizing enterocolitis (NEC), infectious diarrhea, inflammatory bowel disease (IBD), short-bowel syndrome (SBS), neonatal sepsis, gastrointestinal respiratory infections, some minor conditions. discusses clinical trials regarding these conditions which occasionally encountered infants. The anti-inflammatory, antimicrobial, immunomodulatory, antiviral properties discussed, emphasizing mechanisms action. Clinical trials, particularly humans, provide evidence supporting inclusion formulas diets, although precise standards age, feeding time, amounts needed ensure safety efficacy. However, potential adverse effects, allergic reactions caseins immunoglobulin E, must be considered. More comprehensive necessary expand infant feeding, important components BC, should further studied their synergistic diseases. Ultimately, shows promise health incorporated into nutritional supplements caution.

Language: Английский

Antimicrobial Properties of Colostrum and Milk DOI Creative Commons
Furkan Eker, Emir Akdaşçi, Hatice Duman

et al.

Antibiotics, Journal Year: 2024, Volume and Issue: 13(3), P. 251 - 251

Published: March 11, 2024

The growing number of antibiotic resistance genes is putting a strain on the ecosystem and harming human health. In addition, consumers have developed cautious attitude towards chemical preservatives. Colostrum milk are excellent sources antibacterial components that help to strengthen immunity offspring accelerate maturation immune system. It possible study these important defenses colostrum, such as lactoferrin, lysozyme, immunoglobulins, oligosaccharides, etc., biotherapeutic agents for prevention treatment numerous infections caused by microbes. Each has different mechanisms interactions in various places. compound’s action determine where activity appears. activation colostrum compounds can start infant’s mouth during lactation continue gastrointestinal regions. These properties possess potential therapeutic uses. order discover new perspectives methods bacterial infections, additional investigations complexes required.

Language: Английский

Citations

28

A Comprehensive Review of Nanoparticles: From Classification to Application and Toxicity DOI Creative Commons
Furkan Eker, Hatice Duman, Emir Akdaşçi

et al.

Molecules, Journal Year: 2024, Volume and Issue: 29(15), P. 3482 - 3482

Published: July 25, 2024

Nanoparticles are structures that possess unique properties with high surface area-to-volume ratio. Their small size, up to 100 nm, and potential for modifications have enabled their use in a wide range of applications. Various factors influence the applications NPs, including synthesis method physical attributes such as size shape. Additionally, materials used NPs primary determinants application. Based on chosen material, generally classified into three categories: organic, inorganic, carbon-based. These categories include variety materials, proteins, polymers, metal ions, lipids derivatives, magnetic minerals, so on. Each material possesses activity application NPs. Consequently, certain typically particular areas because they higher efficiency along tenable toxicity. Therefore, classification base NP hold significant importance both research In this paper, we discuss these classifications, exemplify most major categorize them according preferred area This review provides an overall application,

Language: Английский

Citations

28

The Impact of Fermentation on the Antioxidant Activity of Food Products DOI Creative Commons
Sümeyye Sarıtaş,

Alicia C. Mondragón Portocarrero,

José Manuel Miranda

et al.

Molecules, Journal Year: 2024, Volume and Issue: 29(16), P. 3941 - 3941

Published: Aug. 21, 2024

From ancient times to the present day, fermentation has been utilized not only for food preservation but also enhancing nutritional and functional properties of foods. This process is influenced by numerous factors, including type microorganisms used, substrate composition, pH, time, temperature, all which can significantly alter characteristics final product. Depending on parameters, enhances bioactive content products imparts necessary properties, such as antioxidant characteristics, be considered functional. The enhancement these particularly activity, enriches foods with compounds attributes, contributing improved health benefits. Through a review recent research, this study elucidates how different processes enhance bioavailability efficacy antioxidants, thereby improving qualities investigated multifaceted effects exploring various types conditions fermentation. It highlights specific examples from dairy other categories well valorization waste byproducts. findings underscore potential sustainable method produce health-promoting elevated activities, offering new perspectives science technology.

Language: Английский

Citations

22

Functional chocolate: exploring advances in production and health benefits DOI Creative Commons
Sümeyye Sarıtaş, Hatice Duman, Burcu Pekdemir

et al.

International Journal of Food Science & Technology, Journal Year: 2024, Volume and Issue: 59(8), P. 5303 - 5325

Published: June 30, 2024

Abstract Chocolate has been a part of human consumption for millennia, serving as confection, medicine and aphrodisiac. is increasing worldwide, independent the age or social background. The substantial content chocolate may provide consumers with antioxidant, anti-inflammatory, antimicrobial, antiallergenic, anticarcinogenic benefits. Beyond such properties, diverse bioactive ingredients are utilised in creation functional products aiming at promoting health meeting modern consumers' demands market orientations. These primarily focused on enhancing nutraceutical effects, antioxidant activity, protein prebiotic effects. Additionally, use A2 milk powder production holds promising expectations towards digestibility products. Due to superior affinity proteolytic enzymes, can be digested more easily than A1 milk. In this way, addition chocolate, it become digestible. objectives review comprehensive understanding evolution consumption, its benefits, contemporary innovations production. potential developing digestible, chocolates made from milk, which could rejuvenate production, discussed article.

Language: Английский

Citations

11

Role of Bovine Colostrum Against Various Diseases DOI
Yalçın Mert Yalçıntaş, Hatice Duman, João Miguel Rocha

et al.

Food Bioscience, Journal Year: 2024, Volume and Issue: 61, P. 104818 - 104818

Published: Aug. 2, 2024

Language: Английский

Citations

11

Exploring the impact of colostrum supplementation on athletes: a comprehensive analysis of clinical trials and diverse properties DOI Creative Commons
Yalçın Mert Yalçıntaş, Barış Baydemir, Hatice Duman

et al.

Frontiers in Immunology, Journal Year: 2024, Volume and Issue: 15

Published: May 10, 2024

Colostrum, an invaluable food produced by mammals during the postnatal period, contains important bioactive components. It is a valuable therapeutic substance that can be used to treat variety of disorders, in addition its primary function providing passive immunity newborns. Undoubtedly, strong dedication intense effort and demanding training schedules necessary succeed today’s sports environment. Peak physical fitness, strategic skill development, mental toughness are highly valued environments which athletes compete. However, inherent difficulties brought about athletes’ matched with character modern sports. The intensity athletic activity frequently provides little time for sufficient relaxation, nutritional preparation, overall recovery, contribute tiredness. Athletes need develop all-encompassing strategies overcome these obstacles. These should prioritize self-care recovery maximizing efficiency. components colostrum bring forth various effects against challenges experienced athletes; including diarrhea, upper respiratory tract infections, muscle injuries, intestinal etc. This review examined different on athletes, effect use as whole performance clinical research conducted this field. While majority studies report positive colostrum, further needed.

Language: Английский

Citations

7

The potential of lactoferrin as antiviral and immune-modulating agent in viral infectious diseases DOI Creative Commons
Furkan Eker, Hatice Duman, Melih Ertürk

et al.

Frontiers in Immunology, Journal Year: 2024, Volume and Issue: 15

Published: Nov. 15, 2024

Emerging infectious diseases are caused by unpredictable viruses with the dangerous potential to trigger global pandemics. These typically initiate infection utilizing anionic structures of host cell surface receptors gain entry. Lactoferrin (Lf) is a multifunctional glycoprotein multiple properties such as antiviral, anti-inflammatory and antioxidant activities. Due its cationic structure, Lf naturally interacts certain receptors, heparan sulfate proteoglycans, well viral particles other that targeted viruses. Therefore, may interfere virus-host interactions acting receptor competitor for Herein we summarize studies in which this competition was investigated SARS-CoV-2, Zika, Dengue, Hepatitis Influenza vitro . have demonstrated not only Lf’s competitive properties, but also intracellular impact on cells, enhancing survival reducing efficiency inhibiting enzymes. In addition, immunomodulatory effect highlighted, it can influence activity specific immune cells regulate cytokine release, thereby host’s response infections. Collectively, these promote promising candidate research diseases.

Language: Английский

Citations

6

Lactoferrin: A Promising Therapeutic Molecule against Human Papillomavirus DOI Open Access
Merve Kaplan, Merve Baktıroğlu, Arda Erkan Kalkan

et al.

Nutrients, Journal Year: 2024, Volume and Issue: 16(18), P. 3073 - 3073

Published: Sept. 12, 2024

Lactoferrin is a multifunctional glycoprotein naturally found in mammalian secretions, predominantly colostrum and milk. As key component of dairy foods, lactoferrin enhances viral protection boosts human health, owing to its fundamental properties including antiviral, anti-inflammatory, immune-modulatory effects. Importantly, the antiviral effect has been shown against range viruses causing serious infections threatening health. One that exerts significant effects on papillomavirus (HPV), which most prevalent transmitted infection affecting myriad people around world. high potential inhibit HPV via different mechanisms, direct binding envelope proteins or their cell receptors, thereby hindering entry immune stimulation by triggering release some immune-related molecules through body, such as lymphocytes. Along with HPV, also can coronaviruses hepatitis same manner. Here, we overview current knowledge other infections.

Language: Английский

Citations

4

Substitutive Effects of Milk vs. Vegetable Milk on the Human Gut Microbiota and Implications for Human Health DOI Open Access
Alicia del Carmen Mondragón, Aroa López-Santamarina, Patricia Regal

et al.

Nutrients, Journal Year: 2024, Volume and Issue: 16(18), P. 3108 - 3108

Published: Sept. 14, 2024

Background: In the last two decades, consumption of plant-based dairy substitutes in place animal-based milk has increased different geographic regions world. Dairy vegetable origin have a quantitative composition macronutrients such as animal milk, although carbohydrates, proteins and fats, well bioactive components, is completely from that milk. Many components been shown to relevant effects on intestinal microbiota. Methods: Therefore, aim this review compare obtained by previous works gut microbiota after ingestion and/or beverages. Results: general, results included studies were very positive for intake. Thus, we found an increase richness diversity, production short-chain fatty acids, beneficial microbes Bifidobacterium, lactobacilli, Akkermansia, Lachnospiraceae or Blautia. other cases, significant decrease potential harmful bacteria Proteobacteria, Erysipelotrichaceae, Desulfovibrionaceae Clostridium perfingens animal-origin Vegetable beverages also generally produced relative presence Bifidobacterium However, some negative results, increases pathogens Enterobacteriaceae, Salmonella Fusobacterium. Conclusions: From perspective their microbiota, milks appear be more human health than substitutes. These should considered those cases where replacement recommended.

Language: Английский

Citations

4

The Impact of Freeze Drying on Bioactivity and Physical Properties of Food Products DOI Creative Commons

Nurten Coşkun,

Sümeyye Sarıtaş, Yassine Jaouhari

et al.

Applied Sciences, Journal Year: 2024, Volume and Issue: 14(20), P. 9183 - 9183

Published: Oct. 10, 2024

Freeze drying (FD) is a technique used to preserve the bioactive content and flavor of samples. Foods with short shelf life due nature have been preserved via FD in recent years. The success thanks high retention ability compounds sample. However, cost energy consumption limit its usage several fields. Freezing, primary drying, secondary which take place same device, are stages FD. In addition, parameters, including pretreatment, size, temperature, sample species, time, pressure, affect process. These parameters controlled increase effectiveness on Moreover, has compared other techniques hot air microwave vacuum solar determine protective capability. It also applied valorization waste products, common problem worldwide. For valorization, microencapsulation powder production achieved using years, studies effects use various materials increased, providing new aspects for future science food industry.

Language: Английский

Citations

4