Antioxidant Activity in Bee Products: A Review

Antioxidants, Journal Year: 2021, Volume and Issue: 10(1), P. 71 - 71

Published: Jan. 7, 2021

Bee products have been used since ancient times both for their nutritional value and a broad spectrum of therapeutic purposes. They are deemed to be potential source natural antioxidants that can counteract the effects oxidative stress underlying pathogenesis many diseases. In view growing interest in using bioactive substances from sources promote health reduce risk developing certain illnesses, this review aims update current state knowledge on antioxidant capacity bee such as honey, pollen, propolis, beeswax, royal jelly venom, analytical methods used. The complex, variable composition these multitude study activities responsible wide range results reported by plethora available studies. This suggests need establish standardized more efficiently evaluate intrinsic characteristics make data obtained comparable.

Language: Английский

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New Insights into the Biological and Pharmaceutical Properties of Royal Jelly

International Journal of Molecular Sciences, Journal Year: 2020, Volume and Issue: 21(2), P. 382 - 382

Published: Jan. 8, 2020

Royal jelly (RJ) is a yellowish-white and acidic secretion of hypopharyngeal mandibular glands nurse bees used to feed young worker larvae during the first three days entire life queen bees. RJ one most appreciated valued natural product which has been mainly in traditional medicines, health foods, cosmetics for long time different parts world. It also studied bee product, aimed at unravelling its bioactivities, such as antimicrobial, antioxidant, anti-aging, immunomodulatory, general tonic action against laboratory animals, microbial organisms, farm clinical trials. commonly supplement various diseases, including cancer, diabetes, cardiovascular, Alzheimer's disease. Here, we highlight recent research advances on main bioactive compounds RJ, proteins, peptides, fatty acids, phenolics, comprehensive understanding biochemistry, biological, pharmaceutical responses human promotion benefits. This potentially important gain novel insight into biological properties RJ.

Language: Английский

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Biological Properties of Vitamins of the B-Complex, Part 1: Vitamins B1, B2, B3, and B5

Nutrients, Journal Year: 2022, Volume and Issue: 14(3), P. 484 - 484

Published: Jan. 22, 2022

This review summarizes the current knowledge on essential vitamins B

Language: Английский

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Health Promoting Properties of Bee Royal Jelly: Food of the Queens

Nutrients, Journal Year: 2021, Volume and Issue: 13(2), P. 543 - 543

Published: Feb. 7, 2021

Royal jelly (RJ) demand is growing every year and so the market for functional foods in general. RJ formed by different substances, mainly carbohydrates, proteins, lipids, but also vitamins, minerals, phenolic or volatile compounds lower proportion. Major royal proteins (MRJP) are, together with 10-hydroxy-2-decenoic acid (10-HDA), key substances of due to their biological properties. In particular, 10-HDA a unique substance this product. has been historically employed as health enhancer still very relevant China traditional medicine apitherapy. Nowadays, it consumed food found supplements other formulations its health-beneficial Within these properites, anti-lipidemic, antioxidant, antiproliferative, antimicrobial, neuroprotective, anti-inflammatory, immunomodulatory, antiaging, estrogenic activities have reported specific components. This manuscript aimed at reviewing current knowledge on components, assessment terms authenticity, activities, related applications.

Language: Английский

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Propolis, Bee Honey, and Their Components Protect against Coronavirus Disease 2019 (COVID-19): A Review of In Silico, In Vitro, and Clinical Studies

Molecules, Journal Year: 2021, Volume and Issue: 26(5), P. 1232 - 1232

Published: Feb. 25, 2021

Despite the virulence and high fatality of coronavirus disease 2019 (COVID-19), no specific antiviral treatment exists until current moment. Natural agents with immune-promoting potentials such as bee products are being explored possible treatments. Bee honey propolis rich in bioactive compounds that express strong antimicrobial, bactericidal, antiviral, anti-inflammatory, immunomodulatory, antioxidant activities. This review examined literature for anti-COVID-19 effects propolis, aim optimizing use these handy prophylactic or adjuvant treatments people infected severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2). Molecular simulations show flavonoids (e.g., rutin, naringin, caffeic acid phenyl ester, luteolin, artepillin C) may inhibit viral spike fusion host cells, viral-host interactions trigger cytokine storm, replication. Similar to potent drug remdesivir, ethanolic extract, liposomes inhibited non-structural proteins SARS-CoV-2 vitro, along naringin infection Vero E6 cells. Propolis extracts delivered by nanocarriers exhibit better against than extracts. In line, hospitalized COVID-19 patients receiving green Brazilian a combination Nigella sativa exhibited earlier clearance, symptom recovery, discharge from hospital well less mortality counterparts standard care alone. Thus, an produce beneficial effects. Implications outcomes issues be considered future studies discussed.

Language: Английский

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Natural Compounds and Products from an Anti-Aging Perspective

Molecules, Journal Year: 2022, Volume and Issue: 27(20), P. 7084 - 7084

Published: Oct. 20, 2022

Aging is a very complex process that accompanied by degenerative impairment in many of the major functions human body over time. This inevitable influenced hereditary factors, lifestyle, and environmental influences such as xenobiotic pollution, infectious agents, UV radiation, diet-borne toxins, so on. Many external internal signs symptoms are related with aging senescence, including skin dryness wrinkles, atherosclerosis, diabetes, neurodegenerative disorders, cancer, etc. Oxidative stress, consequence imbalance between pro- antioxidants, one main provoking factors causing aging-related damages concerns, due to generation highly reactive byproducts oxygen nitrogen species during metabolism, which result cellular damage apoptosis. Antioxidants can prevent these processes extend healthy longevity ability inhibit formation free radicals or interrupt their propagation, thereby lowering level oxidative stress. review focuses on supporting antioxidant system organism balancing diet through consumption necessary amount natural ingredients, vitamins, minerals, polyunsaturated fatty acids (PUFA), essential amino acids, probiotics, plants’ fibers, nutritional supplements, polyphenols, some phytoextracts, drinking water.

Language: Английский

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Bee Products: An Emblematic Example of Underutilized Sources of Bioactive Compounds

Journal of Agricultural and Food Chemistry, Journal Year: 2022, Volume and Issue: 70(23), P. 6833 - 6848

Published: Jan. 2, 2022

Beside honey, honeybees (Apis mellifera L.) are able to produce many byproducts, including bee pollen, propolis, bread, royal jelly, and beeswax. Even if the medicinal properties of these byproducts have been recognized for thousands years by ancient civilizations, in modern era, they a limited use, essentially as nutritional supplements or health products. However, natural products excellent sources bioactive compounds, macro- micronutrients, that, synergistic way, confer multiple biological activities such as, example, antimicrobial, antioxidant, anti-inflammatory properties. This work aims update chemical phytochemical composition beeswax summarize main effects exerted on human health, from anticancer immune-modulatory antidiabetic, hypolipidemic, hypotensive, anti-allergic

Language: Английский

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Honey Bee Products: Preclinical and Clinical Studies of Their Anti-inflammatory and Immunomodulatory Properties

Frontiers in Nutrition, Journal Year: 2022, Volume and Issue: 8

Published: Jan. 3, 2022

Graphical Abstract The anti-inflammatory and immunomodulatory possible mechanisms of action bee products suggested by preclinical clinical studies.

Language: Английский

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Current Status of the Bioactive Properties of Royal Jelly: A Comprehensive Review with a Focus on Its Anticancer, Anti-Inflammatory, and Antioxidant Effects

Molecules, Journal Year: 2023, Volume and Issue: 28(3), P. 1510 - 1510

Published: Feb. 3, 2023

Royal jelly (RJ) has been one of the most widely used natural products in alternative medicine for centuries. Being produced by both hypopharyngeal and mandibular glands, RJ exhibits an extraordinary complexity terms its composition, including proteins, lipids, carbohydrates, polyphenols, vitamins, hormones. Due to heterogeneous structure, displays various functional roles honeybees, being involved nutrition, learning, memory, social behavior. Furthermore, a wide range studies reported therapeutic properties, anticancer, anti-inflammatory, antioxidant activities, name few. In this direction, there is health-related problems which medical area specialists researchers are continuously trying find cure, such as cancer, atherosclerosis, or infertility. For mentioned diseases more, it proven that key player finding valuable treatment. review, great impact agent highlighted, with focus on activities. Moreover, we link apitherapeutic potential discussing composition. Herein, discuss novel present latest research work.

Language: Английский

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Royal Jelly: Biological Action and Health Benefits

International Journal of Molecular Sciences, Journal Year: 2024, Volume and Issue: 25(11), P. 6023 - 6023

Published: May 30, 2024

Royal jelly (RJ) is a highly nutritious natural product with great potential for use in medicine, cosmetics, and as health-promoting food. This bee mixture of important compounds, such proteins, vitamins, lipids, minerals, hormones, neurotransmitters, flavonoids, polyphenols, that underlie the remarkable biological therapeutic activities RJ. Various bioactive molecules like 10-hydroxy-2-decenoic acid (10-HDA), antibacterial protein, apisin, major royal specific peptides apisimin, royalisin, royalactin, apidaecin, defensin-1, jelleins are characteristic ingredients RJ shows numerous physiological pharmacological properties, including vasodilatory, hypotensive, antihypercholesterolaemic, antidiabetic, immunomodulatory, anti-inflammatory, antioxidant, anti-aging, neuroprotective, antimicrobial, estrogenic, anti-allergic, anti-osteoporotic, anti-tumor effects. Moreover, may reduce menopause symptoms improve health reproductive system, liver, kidneys, promote wound healing. article provides an overview molecular mechanisms underlying beneficial effects various diseases, aging, aging-related complications, special emphasis on components their properties. The data presented should be incentive future clinical studies hopefully will advance our knowledge about facilitate development novel RJ-based opportunities improving human well-being.

Language: Английский

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