CB1R chronic intermittent pharmacological activation facilitates amphetamine seeking and self-administration and changes in CB1R/CRFR1 expression in the amygdala and nucleus accumbens in rats DOI

Rodolfo Sánchez‐Zavaleta,

Lorena Alline Becerril-Meléndez, Alejandra E. Ruíz-Contreras

et al.

Pharmacology Biochemistry and Behavior, Journal Year: 2023, Volume and Issue: 227-228, P. 173587 - 173587

Published: June 1, 2023

Language: Английский

Food and alcohol disturbance among people who have undergone bariatric surgery DOI Creative Commons
Gretchen E. White, Mai‐Ly N. Steers, Karla Bernardi

et al.

Obesity Science & Practice, Journal Year: 2024, Volume and Issue: 10(1)

Published: Jan. 30, 2024

There have been numerous investigations of aberrant eating and substance abuse among patients who undergone bariatric surgery, which affects the metabolism pharmacokinetics alcohol. However, there is a dearth literature considering complex interplay between changes in post-surgery food alcohol consumption. Furthermore, despite increasing recognition issues surrounding replacing consumption with (Food Alcohol Disturbance [FAD]), most emerging research has focused on young adult populations. This perspective reviews synthesizes small but growing body consumption, particularly FAD, considers its application to surgery general. are unique considerations for surgery. Patients experience altered gastric anatomy, metabolism, advised abstain from drinking after After reviewing available literature, this highlights future directions practice

Language: Английский

Citations

4

Liver and Atherosclerotic Risk of Alcohol Consumption in Patients with Metabolic Dysfunction-Associated Steatotic Liver Disease DOI
Shaowen Wang,

C. H. Wang,

Yu‐Ming Cheng

et al.

Atherosclerosis, Journal Year: 2025, Volume and Issue: 403, P. 119161 - 119161

Published: March 7, 2025

Language: Английский

Citations

0

Anti-inflammatory, antithrombotic and anti-oxidant bioactives of beer and brewery by-products, as ingredients of bio-functional foods, nutraceuticals, cosmetics, cosmeceuticals and pharmaceuticals with health promoting properties DOI Creative Commons
Αλέξανδρος Τσούπρας, Eirini A. Panagopoulou, George Z. Kyzas

et al.

AIMS Agriculture and Food, Journal Year: 2024, Volume and Issue: 9(2), P. 568 - 606

Published: Jan. 1, 2024

<abstract> <p>Fermented alcoholic beverages and their by-products, including beer breweries' bio-wastes like spent yeasts, grain, hops, contain a plethora of natural bioactive compounds that have recently gained attention for valorization as functional ingredients in several novel foods nutraceuticals, well drugs cosmetics applications. Within this article, the bio-functional fermented product by-products with anti-inflammatory, antithrombotic, anti-oxidant bioactivities are thoroughly reviewed. The important roles yeasts involved such bioactives to be present brewery also outlined. health promoting benefits moderate consumption resulting from these bioactives, part balanced diet, against inflammation-related chronic disorders is discussed, along detrimental effects abuse potential alternative non-alcoholic beers. mechanisms action synergism anti-thrombotic, antioxidant properties presented. Current research future perspectives on valorizing grain hops health-promoting foods, supplements, nutraceuticals cosmetics, cosmeceuticals, pharmaceuticals evaluated, while limitations use discussed.</p> </abstract>

Language: Английский

Citations

2

Beneficial Effects of Beer, Brewery By-Products, and Their Bioactives: Potential Applications in Novel Health-Promoting Products DOI
Αλέξανδρος Τσούπρας, Despina A. Gkika,

Theodoros Markopoulos

et al.

Reference series in phytochemistry, Journal Year: 2024, Volume and Issue: unknown, P. 1 - 61

Published: Jan. 1, 2024

Language: Английский

Citations

2

The Human Body as an Ethanol-Producing Bioreactor—The Forensic Impacts DOI Creative Commons
Ivan Šoša

Fermentation, Journal Year: 2023, Volume and Issue: 9(8), P. 738 - 738

Published: Aug. 7, 2023

Auto-brewery syndrome (ABS), also called gut fermentation syndrome, is an extremely infrequent but underrecognized disorder where ethanol produced endogenously, similar to a typical bioreactor. The reliability of forensic alcohol analysis results frequently challenged as the concentration in breath, blood, and/or urine constitutes important evidence for prosecuting drivers under influence alcohol. This further emphasizes need understand ABS, legal proceedings it often presented grounds acquittal due concept that findings could have corresponded endogenously ethanol. However, this rare and underdiagnosed medical condition should not be considered purely lawyer’s favorite argument. Manifestations ABS can severe impact on patient’s life pose social consequences well. Unfortunately, barely anything has been unearthed, aspects such genetic susceptibility, gut-mucus-eating microorganisms, fecal microbiome transplantation were reviewed first time context. framework review was limited microbiota exclusively; moreover, overgrowth microorganisms linked use antibiotics. Studies indicated carbohydrate occurs locations other than intra-intestinal flora. Accordingly, literature searched cases patients with yeast infections their genitourinary or oral systems.

Language: Английский

Citations

6

Associations between Liver Enzymes, Lifestyle Risk Factors and Pre-Existing Medical Conditions in a Population-Based Cross-Sectional Sample DOI Open Access
Onni Niemelä,

Aini Bloigu,

Risto Bloigu

et al.

Journal of Clinical Medicine, Journal Year: 2023, Volume and Issue: 12(13), P. 4276 - 4276

Published: June 26, 2023

While alanine aminotransferase (ALT) and gamma-glutamyltransferase (GGT) enzymes are commonly used indicators of liver dysfunction recent studies have suggested that these may also serve as predictive biomarkers in the assessment extrahepatic morbidity. In order to shed further light on interactions between serum enzyme abnormalities, factors lifestyle health status we examined ALT GGT activities a population-based sample 8743 adult individuals (4048 men, 4695 women from National FINRISK 2002 Study, mean age 48.1 ± 13.1 years) with different levels alcohol drinking, smoking, physical activity, body weight presence or absence various pre-existing medical conditions. The assessments included laboratory tests for inflammation, lipid fatty index (FLI), proxy liver. prevalence abnormalities were significantly influenced by use (ALT: p < 0.0005 men; GGT: <0.0005 both genders), smoking (GGT: =0.002 women), adiposity (p all comparisons), inactivity <0.0005; ALT: <0.05 women) coffee consumption genders; <0.001 men). total sum risk factor scores (LRFS) occurrence rather linear manner. Significantly higher LRFS observed subgroups conditions when compared those having no morbidities <0.0005). logistic regression analyses adjusted factors, associated liver, diabetes hypertension. coronary heart disease, angina pectoris, cardiac insufficiency, cerebrovascular asthma depression. Combinations abnormal increased odds hypertension coinciding FLI. data indicates readily respond unfavorable associating wide array supports close links hepatic open new insights more comprehensive algorithms assessing mechanistically anchored disease

Language: Английский

Citations

4

Diet affects inflammatory arthritis: a Mendelian randomization study of 30 dietary patterns causally associated with inflammatory arthritis DOI Creative Commons
Haiyang Wang,

Qing-lin Wu,

Pengda Qu

et al.

Frontiers in Nutrition, Journal Year: 2024, Volume and Issue: 11

Published: July 17, 2024

The causal associations between dietary intake and the risk severity of Inflammatory Arthritis (IA) are currently unknown.

Language: Английский

Citations

1

Impact of Physical Activity on the Characteristics and Metabolic Consequences of Alcohol Consumption: A Cross-Sectional Population-Based Study DOI Open Access
Onni Niemelä,

Aini Bloigu,

Risto Bloigu

et al.

International Journal of Environmental Research and Public Health, Journal Year: 2022, Volume and Issue: 19(22), P. 15048 - 15048

Published: Nov. 15, 2022

Sedentary lifestyle and excessive alcohol drinking are major modifiable risk factors of health. In order to shed further light on the relationships between physical activity health consequences intake, we measured biomarkers liver function, inflammation, lipid status fatty index tests in a large population-based sample individuals with different levels activity, other factors. The study included 21,050 adult participants (9940 men, 11,110 women) (mean age 48.2 ± 13.3 years) National FINRISK Study. Data drinking, smoking body weight were recorded. classified subgroups according gender, (sedentary, low, moderate, vigorous, extreme), (abstainers, moderate drinkers, heavy drinkers) patterns (regular or binge, types beverages preferred consumption). Serum enzymes (GGT, ALT), C-reactive protein (CRP) profiles using standard laboratory techniques. Physical was linearly inversely related amount consumption, lowest being observed those vigorous extreme (p < 0.0005). Physically active less frequently binge-type cigarette smokers coffee drinkers than sedentary 0.0005 for linear trend all comparisons). General Linear Model assess main interaction effects consumption biomarker status, as adjusted anthropometric measures, increasing found be associated more favorable findings serum GGT 0.0005), ALT men), cholesterol = 0.025 men; p women), HDL-cholesterol 0.001 LDL-cholesterol 0.03 triglycerides CRP 0.006 data support view that regular may counteract adverse metabolic inflammation status. role should emphasized interventions aimed at reducing problems unfavorable lifestyle.

Language: Английский

Citations

7

Enhancement of the Functional Properties of Mead Aged with Oak (Quercus) Chips at Different Toasting Levels DOI Creative Commons
Juciane Prois Fortes, Fernanda Wouters Franco, Júlia Baranzelli

et al.

Molecules, Journal Year: 2022, Volume and Issue: 28(1), P. 56 - 56

Published: Dec. 21, 2022

Consumers increasingly prefer and seek functional beverages, which, given their characteristics, provide important bioactive compounds that help prevent treat chronic diseases. Mead is a traditional fermented alcoholic beverage made from honey solution. The aging process of mead with oak chips innovative bestows characteristics to this beverage. Thus, in study, we sought develop characterize novel by combining the health benefits beverages wood. Phenolic compounds, flavonoids, antioxidant capacity were analyzed using at different toasting levels aged for 360 days. LC-ESI-QTOF-MS/MS was used analyze chemical profile meads. Over time, showed higher total phenolic flavonoid content capacity. Eighteen belonging classes organic acids, tannins identified meads after Our findings revealed addition during contributed p-coumaric, ellagic, abscisic, chlorogenic naringenin, vanillin, tiliroside significantly impacted quality mead.

Language: Английский

Citations

7

Associations of Adherence to the 2018 World Cancer Research Fund and the American Institute for Cancer Research Dietary Recommendations with Gut Microbiota and Inflammation Levels DOI Open Access
Dan Wang,

Sijia Meng,

Jiqiu Li

et al.

Nutrients, Journal Year: 2023, Volume and Issue: 15(17), P. 3705 - 3705

Published: Aug. 24, 2023

Whether the World Cancer Research Fund and American Institute for (WCRF/AICR) dietary recommendations affect gut microbiota inflammatory status remains unclear. We examined association of adherence scores to WCRF/AICR with inflammation in a cross-sectional setting.The diet were calculated 151 participants (adenoma 97, non-adenoma 54) from 7-day records. The was analyzed by 16S rRNA gene sequencing fecal samples. levels biomarkers both blood (i.e., IL-6, IL-8, IgA, IgM, IgG) samples FCP) evaluated 97 colorectal adenoma patients who had available. Multivariable linear regression analyses conducted examine individual total biomarker levels.Participants higher lower relative abundance Proteobacteria (β = -0.041, 95%CI: -0.073, -0.009), Enterobacteriaceae -0.035, -0.067, -0.003), unidentified at genus level -0.029, -0.055, -0.003) compared those adherence. Plant-based food intake positively correlated increased Phascolarctobacterium 0.013, 0.001, 0.026). Restricting fast linked high Bacteroidaceae 0.149, 0.040, 0.257) Bacteroides 0.257). Limiting sugary drinks associated reduced Lachnospiraceae -0.155, -0.292, -0.018). -0.251, -0.450, -0.052) restriction -0.226, -0.443, -0.008) IGG men. Alcohol IL-6 -7.095, -11.286, -2.903) IL-8 -7.965, -14.700, -1.230) women, but 0.918, 0.161, 1.675) men.Our findings support inflammation. These results need be validated additional prospective or interventional studies.

Language: Английский

Citations

3