Nutrients,
Journal Year:
2024,
Volume and Issue:
16(2), P. 265 - 265
Published: Jan. 16, 2024
This
narrative
review
delves
into
the
intricate
relationship
between
irritable
bowel
syndrome
(IBS)
and
food
intolerances.
IBS,
a
chronic
functional
gastrointestinal
disorder,
is
characterized
by
symptoms
like
abdominal
pain
altered
habits.
The
prevalence
of
IBS
has
increased
globally,
especially
among
young
adults.
Food
dietary
habits
play
crucial
role
in
management.
About
85-90%
patients
report
symptom
exacerbation
linked
to
specific
consumption,
highlighting
strong
connection
intolerances
IBS.
often
exhibit
dose-dependent
pattern,
posing
challenge
identifying
trigger
foods.
issue
further
complicated
complex
nature
physiology
varying
compositions.
discusses
various
patterns
their
impact
on
including
low-FODMAP
diet,
gluten-free
Mediterranean
diet.
It
highlights
importance
personalized
approach
management,
considering
individual
variability
history.
In
conclusion,
this
emphasizes
need
for
accurate
diagnosis
holistic
management
interplay
factors
pathophysiology.
underlines
patient
education
adherence
treatment
plans,
acknowledging
challenges
posed
triggers
psychological
restrictions.
Nutrients,
Journal Year:
2023,
Volume and Issue:
15(20), P. 4466 - 4466
Published: Oct. 21, 2023
The
gut
microbiome
is
a
diverse
bacterial
community
in
the
human
gastrointestinal
tract
that
plays
important
roles
variety
of
biological
processes.
Short-chain
fatty
acids
(SCFA)
are
produced
through
fermentation
dietary
fiber.
Certain
microbes
responsible
for
producing
SCFAs
such
as
acetate,
propionate
and
butyrate.
An
imbalance
diversity
can
lead
to
metabolic
disorders
inflammation-related
diseases.
Changes
SCFA
levels
associated
microbiota
were
observed
IBD,
suggesting
an
association
between
disease.
affect
reactive
oxygen
species
(ROS)
with
IBD.
Gut
closely
related
it
study
them
further.
Nutrients,
Journal Year:
2024,
Volume and Issue:
16(3), P. 400 - 400
Published: Jan. 30, 2024
The
infant
gut
microbiome
plays
a
key
role
in
the
healthy
development
of
human
organism
and
appears
to
be
influenced
by
dietary
practices
through
multiple
pathways.
First,
maternal
diet
during
pregnancy
nutrition
significantly
influence
microbiota.
Moreover,
breastfeeding
fosters
proliferation
beneficial
bacteria,
while
formula
feeding
increases
microbial
diversity.
timing
introducing
solid
foods
also
influences
microbiota
composition.
In
preterm
infants
is
factors,
including
time
since
birth
intake
breast
milk,
interventions
such
as
probiotics
prebiotics
supplementation
show
promising
results
reducing
morbidity
mortality
this
population.
These
findings
underscore
need
for
future
research
understand
long-term
health
impacts
these
further
strategies
enrich
formula-fed
infants.
Nutrients,
Journal Year:
2024,
Volume and Issue:
16(3), P. 370 - 370
Published: Jan. 26, 2024
The
low
FODMAP
(fermentable
oligosaccharide,
disaccharide,
monosaccharide,
and
polyol)
diet
is
a
beneficial
therapeutic
approach
for
patients
with
irritable
bowel
syndrome
(IBS).
However,
how
the
works
still
not
completely
understood.
These
mechanisms
encompass
only
traditionally
known
factors
such
as
luminal
distension
induced
by
gas
water
but
also
recent
evidence
on
role
of
FOMAPs
in
modulation
visceral
hypersensitivity,
increases
intestinal
permeability,
induction
microbiota
changes,
production
short-chain
fatty
acids
(SCFAs),
well
metabolomics
alterations
motility.
Although
most
supporting
quality,
trials
have
confirmed
its
effectiveness,
even
though
majority
pertains
to
restriction
phase
effectiveness
relieving
abdominal
bloating
pain.
This
review
examines
potential
pathophysiological
provides
an
overview
existing
across
various
IBS
subtypes.
Key
considerations
use
include
challenges
disadvantages
associated
practical
implementation,
including
need
professional
guidance,
variations
individual
responses,
concerns
related
microbiota,
nutritional
deficiencies,
development
constipation,
necessity
excluding
eating
disorder
before
commencing
diet,
scarcity
long-term
data.
Despite
recognized
efficacy
symptom
management,
acknowledging
these
limitations
becomes
imperative
nuanced
comprehension
managing
IBS.
By
investigating
subtypes
addressing
emerging
modulations
alongside
limitations,
this
aims
serve
valuable
resource
healthcare
practitioners,
researchers,
navigating
intricate
landscape
Current Issues in Molecular Biology,
Journal Year:
2024,
Volume and Issue:
46(3), P. 2658 - 2677
Published: March 21, 2024
Microplastics
and
nanoplastics
(MNPs)
are
becoming
an
increasingly
severe
global
problem
due
to
their
widespread
distribution
complex
impact
on
living
organisms.
Apart
from
environmental
impact,
the
effects
of
MNPs
organisms
have
also
continued
attract
attention.
The
harmful
has
been
extensively
documented
in
marine
invertebrates
larger
vertebrates
like
fish.
However,
research
toxicity
these
particles
mammals
is
still
limited,
possible
humans
poorly
understood.
Considering
that
commonly
found
food
or
packaging,
primarily
exposed
them
through
ingestion.
It
would
be
valuable
investigate
potential
gut
health.
This
review
focuses
recent
exploring
toxicological
impacts
micro-
gut,
as
observed
human
cell
lines
mammalian
models.
Available
data
various
studies
indicate
accumulation
models
cells
may
result
adverse
consequences,
terms
epithelial
toxicity,
immune
disruption
microbiota.
paper
discusses
current
limitations
prospects
this
field,
aiming
provide
a
scientific
basis
reference
for
further
toxic
mechanisms
nanoplastics.
International Journal of Molecular Sciences,
Journal Year:
2024,
Volume and Issue:
25(17), P. 9366 - 9366
Published: Aug. 29, 2024
The
human
gastrointestinal
tract
hosts
a
complex
and
dynamic
community
of
microorganisms
known
as
the
gut
microbiota,
which
play
pivotal
role
in
numerous
physiological
processes,
including
digestion,
metabolism,
immune
function.
Recent
research
has
highlighted
significant
impact
diet
on
microbiota
composition
functionality,
consequential
effects
host
health.
Concurrently,
there
is
growing
evidence
linking
to
inflammation,
key
factor
many
chronic
diseases
such
inflammatory
bowel
disease
(IBD),
obesity,
diabetes,
cardiovascular
(CVDs).
This
review
explores
how
dietary
components
influence
composition,
these
microbial
changes
affect
pathways,
therapeutic
implications
modulating
this
axis
for
prevention
management.
Beneficial
patterns,
Mediterranean
(MD)
plant-based
diets,
promote
diverse
balanced
supporting
anti-inflammatory
pathways.
Conversely,
Western
(WD),
high
saturated
fats
refined
sugars,
associated
with
dysbiosis
increased
inflammation.
With
all
links
between
three
variables
considered,
attempts
offer
thorough
examination
triangle
formed
by
food.
Trends in Microbiology,
Journal Year:
2024,
Volume and Issue:
32(11), P. 1106 - 1118
Published: May 9, 2024
The
human
gastrointestinal
microbiome
encompasses
bacteria,
fungi,
and
viruses
forming
complex
bionetworks
which,
for
organismal
health,
must
be
in
a
state
of
homeostasis.
An
important
homeostatic
mechanism
derives
from
microbial
competition,
which
maintains
the
relative
abundance
species
healthy
balance.
Microbes
compete
nutrients
secrete
metabolites
that
inhibit
other
microbes.
Short-chain
fatty
acids
(SCFAs)
are
one
such
class
made
by
gut
bacteria
to
very
high
levels.
SCFAs
metabolised
microbes
host
cells
have
multiple
roles
regulating
cell
physiology.
Here,
we
review
mechanisms
regulate
fungal
commensal
Candida
albicans.
We
discuss
SCFA's
ability
growth,
limit
invasive
behaviours
modulate
surface
antigens
recognised
immune
cells.
underlying
these
roles:
regulation
gene
expression,
metabolism,
signalling
SCFA-driven
post-translational
protein
modifications
acylation,
contribute
changes
acylome
dynamics
C.
albicans
with
potentially
large
consequences
Given
mycobiome
is
reservoir
systemic
disease
has
also
been
implicated
inflammatory
bowel
disease,
understanding
bacterial
metabolites,
as
SCFAs,
control
might
provide
therapeutic
avenues.
Heliyon,
Journal Year:
2024,
Volume and Issue:
10(13), P. e33905 - e33905
Published: July 1, 2024
BackgroundFish
contains
high-quality
omega-3
fatty
acids,
protein,
vitamins,
and
minerals
due
to
this
it
is
termed
as
an
essential
component
of
a
balanced
diet.
But
there
have
been
concerns
raised
about
the
risks
consuming
fish
that
contaminated
with
toxins
such
methylmercury,
polychlorinated
biphenyls
(PCBs),
dioxins,
pesticides,
plastic
waste.
Consumption
containing
these
pollutants
raising
global
mortality
morbidity
rates.Scope
approachesThe
review
examines
current
research
outputs
on
health
benefits
potential
consumption.
The
also
discusses
various
approaches
mitigating
problems
caused
by
consumption,
highlights
roles
balancing
when
fish.Key
findings
conclusionDifferent
indicated
contaminants
cause
cancer,
kidney
failure,
adverse
neurological
effect,
cardiovascular
diseases,
so
vulnerable
groups
pregnant,
child
breast-feeding
children.
In
conclusion,
need
get
more
tangible
evidence
advantages
disadvantages
consumption
safeguard
wellbeing
society.
Gastrointestinal Disorders,
Journal Year:
2025,
Volume and Issue:
7(1), P. 7 - 7
Published: Jan. 15, 2025
The
human
microbiome,
a
complex
ecosystem
of
microorganisms
residing
in
and
on
the
body,
plays
pivotal
role
regulation
wide
range
physiological
processes,
including
digestion,
immune
responses,
metabolic
functions.
In
recent
years,
rapidly
growing
field
microbiome-driven
therapeutics
has
garnered
significant
attention
owing
to
its
potential
revolutionize
healthcare.
This
review
explores
evolving
landscape
microbiome-based
therapies,
with
particular
focus
gut
microbiome
implications
for
both
health
precision
medicine.
We
highlight
advances
understanding
how
microbial
communities
influence
disease
pathogenesis
treatment
outcomes,
spanning
conditions
such
as
inflammatory
bowel
(IBD),
disorders,
neurological
diseases,
even
cancer.
article
also
discusses
emerging
therapeutic
strategies,
probiotics,
prebiotics,
fecal
microbiota
transplantation
(FMT),
microbial-based
drugs,
well
challenges
associated
their
clinical
implementation.
Additionally,
we
examined
integration
profiling
metagenomic
data
is
advancing
medicine,
paving
way
personalized
effective
treatments.
serves
comprehensive
resource
that
synthesizes
current
knowledge,
identifies
key
gaps
research,
offers
insights
into
future
direction
therapeutics,
thus
providing
valuable
framework
clinicians,
researchers,
policymakers
seeking
harness
microbiomes
advance
healthcare
solutions.