Biomedical materials for wound dressing: recent advances and applications

RSC Advances, Journal Year: 2023, Volume and Issue: 13(8), P. 5509 - 5528

Published: Jan. 1, 2023

Wound healing is vital to maintain the physiological functions of skin.

Language: Английский

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Biomaterials-Based Regenerative Strategies for Skin Tissue Wound Healing

ACS Applied Bio Materials, Journal Year: 2022, Volume and Issue: 5(5), P. 2069 - 2106

Published: April 22, 2022

Skin tissue wound healing proceeds through four major stages, including hematoma formation, inflammation, and neo-tissue culminates with remodeling. These steps significantly overlap each other are aided by various factors such as cells, cytokines (both anti- pro-inflammatory), growth that aid in the formation. In all these advanced biomaterials provide several functional advantages, removing exudates, providing cover, transporting oxygen to site, preventing infection from microbes. addition, serve vehicles carry proteins/drug molecules/growth and/or antimicrobial agents target site. this review, we report recent advancements biomaterials-based regenerative strategies augment skin process. conjunction medical sciences, designing nanoengineered is gaining significant attention for numerous functionalities trigger repair. regard, highlight advent of nanomaterial-based constructs healing, especially those being evaluated clinical settings. Herein, also emphasize competence versatility three-dimensional (3D) bioprinting technique management. Finally, discuss challenges perspective biomaterial-based dressings, along prospective future directions. With utilize a cocktail cell sources, agents, drugs, factors, it expected patient-specific will be developed near future, resulting complete no scar

Language: Английский

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An Up-to-Date Review of Biomaterials Application in Wound Management

Polymers, Journal Year: 2022, Volume and Issue: 14(3), P. 421 - 421

Published: Jan. 21, 2022

Whether they are caused by trauma, illness, or surgery, wounds may occur throughout anyone's life. Some injuries' complexity and healing difficulty pose important challenges in the medical field, demanding novel approaches wound management. A highly researched possibility is applying biomaterials various forms, ranging from thin protective films, foams, hydrogels to scaffolds textiles enriched with drugs nanoparticles. The synergy of biocompatibility cell proliferative effects these materials reflected a more rapid rate improved structural functional properties newly grown tissue. This paper aims present biomaterial dressings suitable for management application, reviewing most recent studies field.

Language: Английский

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Recent Advances in Cellulose-Based Hydrogels for Tissue Engineering Applications

Polymers, Journal Year: 2022, Volume and Issue: 14(16), P. 3335 - 3335

Published: Aug. 16, 2022

In recent years, cellulose has attracted much attention because of its excellent properties, such as hydrophilicity, mechanical biodegradability, biocompatibility, low cost and toxicity. addition, derivatives contain abundant hydrophilic functional groups (such hydroxyl, carboxyl aldehyde groups), which are good raw materials for synthesizing biocompatible hydrogels. this paper, the application prospects derivatives-based hydrogels in biomedical tissue engineering summarized discussed through analysis research. Firstly, we discuss structure properties cellulose, nano celluloses (NC) from different sources (including nanocrystals (CNC), nanofibrils (CNF) bacterial (BNC)) ethers esters) obtained by modification methods. Then, preparation methods physical chemical described, respectively. The cellulose-based a scaffold (skin, bone cartilage) field is introduced. Finally, challenges summarized.

Language: Английский

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Bacterial Cellulose—A Remarkable Polymer as a Source for Biomaterials Tailoring

Materials, Journal Year: 2022, Volume and Issue: 15(3), P. 1054 - 1054

Published: Jan. 29, 2022

Nowadays, the development of new eco-friendly and biocompatible materials using 'green' technologies represents a significant challenge for biomedical pharmaceutical fields to reduce destructive actions scientific research on human body environment. Thus, bacterial cellulose (BC) has central place among these novel tailored biomaterials. BC is non-pathogenic bacteria-produced polysaccharide with 3D nanofibrous structure, chemically identical plant cellulose, but exhibiting greater purity crystallinity. Bacterial possesses excellent physicochemical mechanical properties, adequate capacity absorb large quantity water, non-toxicity, chemical inertness, biocompatibility, biodegradability, proper form films stabilize emulsions, high porosity, surface area. Due its suitable characteristics, this ecological material can combine multiple polymers diverse bioactive agents develop composites. alone, mixtures, exhibits numerous applications, including in food electronic industries biotechnological areas (such as wound dressing, tissue engineering, dental implants, drug delivery systems, cell culture). This review presents an overview main properties uses latest promising future such biological diagnosis, biosensors, personalized regenerative medicine, nerve ocular engineering.

Language: Английский

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Recent advances in 3D printing for wound healing: A systematic review

Journal of Drug Delivery Science and Technology, Journal Year: 2022, Volume and Issue: 74, P. 103564 - 103564

Published: July 6, 2022

The advances in additive manufacturing over the past decade have led to development of innovative strategies several healthcare sectors. treatment and healing chronic wounds remains a major clinical challenge due insufficient healing, increasing number patients financial burden systems. use novel natural or synthetic biomaterials design cell-laden bioinks combined with drug substances has paved way for effective wound management including engineering skin substitutes regeneration. advantages printing technologies encompass combination unlimited bioactive molecules cells polymers, fabrication complex scaffold designs, accelerated times personalised dressings. This review highlights principles processes used technological processing limitations. We also provide current trends improvements focusing on materials antimicrobial, antioxidant properties incorporation peptides wounds. Finally, we present approaches tissue regeneration based 3D printing.

Language: Английский

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Novel carboxymethyl cellulose based nanocomposite: A promising biomaterial for biomedical applications

Process Biochemistry, Journal Year: 2023, Volume and Issue: 130, P. 211 - 226

Published: April 3, 2023

Language: Английский

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Stimuli-responsive polysaccharide-based smart hydrogels for diabetic wound healing: Design aspects, preparation methods and regulatory perspectives

Carbohydrate Polymers, Journal Year: 2023, Volume and Issue: 324, P. 121537 - 121537

Published: Nov. 2, 2023

Language: Английский

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A double-layer cellulose/pectin-soy protein isolate-pomegranate peel extract micro/nanofiber dressing for acceleration of wound healing

International Journal of Biological Macromolecules, Journal Year: 2023, Volume and Issue: 255, P. 128198 - 128198

Published: Nov. 20, 2023

Language: Английский

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Developing multifunctional cellulose derivatives for environmental and biomedical applications: Insights into modification processes and advanced material properties

International Journal of Biological Macromolecules, Journal Year: 2024, Volume and Issue: 278, P. 134695 - 134695

Published: Aug. 14, 2024

Language: Английский

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