Diabetes & Metabolism Journal,
Journal Year:
2023,
Volume and Issue:
47(2), P. 201 - 210
Published: Feb. 8, 2023
Background:
We
evaluated
the
validity
and
reliability
of
operational
definition
type
2
diabetes
mellitus
(T2DM)
based
on
Korean
National
Health
Insurance
Service
(NHIS)
database.Methods:
Adult
subjects
(≥40
years
old)
included
in
Korea
Nutrition
Examination
Survey
(KNHANES)
from
2008
to
2017
were
merged
with
those
NHIS
health
check-up
database,
producing
a
cross-sectional
dataset.
sensitivity,
specificity,
accuracy,
agreement
criteria
for
defining
T2DM
by
comparing
them
KNHANES
as
standard
reference.Results:
In
study
population
(n=13,006),
two
algorithms
devised
determine
dataset
whether
diagnostic
claim
codes
accompanied
prescription
anti-diabetic
drugs
(algorithm
1)
or
not
2).
Using
these
algorithms,
prevalence
was
14.9%
(n=1,942;
algorithm
20.8%
(n=2,707;
Good
observed
both
(Kappa
index,
0.73
[algorithm
1],
0.63
2]).
However,
accuracy
(0.93
vs.
0.89)
specificity
(0.96
0.90)
tended
be
higher
1
than
2.
The
(accuracy,
ranging
0.91
0.95)
0.68
0.78)
independent
age,
sex,
socioeconomic
status,
hypertension
dyslipidemia.Conclusion:
population-based
claims
data,
including
codes,
could
valid
tool
identify
individuals
population.
Plants,
Journal Year:
2022,
Volume and Issue:
11(20), P. 2722 - 2722
Published: Oct. 14, 2022
Diabetes
is
a
common
metabolic
disorder
marked
by
unusually
high
plasma
glucose
levels,
which
can
lead
to
serious
consequences
such
as
retinopathy,
diabetic
neuropathy
and
cardiovascular
disease.
One
of
the
most
efficient
ways
reduce
postprandial
hyperglycemia
(PPHG)
in
diabetes
mellitus,
especially
insulin-independent
lower
amount
that
absorbed
inhibiting
carbohydrate
hydrolyzing
enzymes
digestive
system,
α-glucosidase
α-amylase.
α-Glucosidase
crucial
enzyme
catalyzes
final
stage
digestion.
As
result,
inhibitors
slow
D-glucose
release
from
complex
carbohydrates
delay
absorption,
resulting
levels
control
PPHG.
Many
attempts
have
been
made
recent
years
uncover
natural
sources
build
physiologic
functional
diet
or
compound
for
treatment.
phytoconstituent
identified
plants,
including
alkaloids,
flavonoids,
anthocyanins,
terpenoids,
phenolic
compounds,
glycosides
others.
The
current
review
focuses
on
updates
different
traditional/medicinal
plant
extracts
isolated
compounds’
biological
activity
help
development
potent
therapeutic
medications
with
greater
efficacy
safety
treatment
type
2
avoid
For
this
purpose,
we
provide
summary
latest
scientific
literature
findings
well
plant-derived
bioactive
compounds
potential
hypoglycemic
effects.
Moreover,
elucidates
structural
insights
key
drug
target,
enzymes,
its
interaction
inhibitors.
Diabetes & Metabolism Journal,
Journal Year:
2022,
Volume and Issue:
46(4), P. 552 - 563
Published: July 28, 2022
Recently,
medical
research
using
big
data
has
become
very
popular,
and
its
value
increasingly
recognized.
The
Korean
National
Health
Information
Database
(NHID)
is
representative
of
that
combines
information
obtained
from
the
Insurance
Service
collected
for
claims
reimbursement
health
care
services
results
general
examinations
provided
to
all
adults.
This
database
several
strengths
limitations.
Given
large
size,
various
laboratory
data,
questionnaires
check-ups,
their
longitudinal
nature,
long-term
accumulation
since
2002,
carefully
designed
studies
may
provide
valuable
difficult
obtain
other
forms
research.
However,
consideration
possible
bias
careful
interpretation
when
defining
causal
relationships
also
important
because
were
not
purposes.
After
NHID
became
publicly
available,
publications
based
on
this
have
increased
explosively,
especially
in
field
diabetes
metabolism.
article
reviews
history,
structure,
characteristics
NHID.
Recent
trends
database,
commonly
used
operational
diagnosis,
been
introduced.
We
expect
further
progress
expansion
Diabetes & Metabolism Journal,
Journal Year:
2023,
Volume and Issue:
47(5), P. 575 - 594
Published: Sept. 26, 2023
In
May
2023,
the
Committee
of
Clinical
Practice
Guidelines
Korean
Diabetes
Association
published
revised
clinical
practice
guidelines
for
adults
with
diabetes
and
prediabetes.
We
incorporated
latest
research
findings
through
a
comprehensive
systematic
literature
review
applied
them
in
manner
suitable
population.
These
are
designed
all
healthcare
providers
nationwide,
including
physicians,
experts,
certified
educators
who
manage
patients
or
individuals
at
risk
developing
diabetes.
Based
on
recent
changes
international
results
epidemiological
study,
recommended
age
screening
has
been
lowered.
collaboration
relevant
medical
societies,
recently
managing
hypertension
dyslipidemia
have
into
this
guideline.
An
abridgment
containing
practical
information
patient
education
management
clinic
was
separately.
BMJ,
Journal Year:
2024,
Volume and Issue:
unknown, P. e076388 - e076388
Published: Feb. 13, 2024
Abstract
Objective
To
investigate
the
risk
of
non-alcoholic
fatty
liver
disease
(NAFLD)
for
cardiovascular
and
all
cause
death
in
patients
with
type
2
diabetes
mellitus
(T2DM).
Design
Nationwide
population
based
study.
Setting
Longitudinal
cohort
study
Korea.
Participants
7
796
763
participants
National
Health
Screening
Programme
2009
were
divided
into
three
groups
on
NAFLD
status:
no
(fatty
index<30);
grade
1
(30≤fatty
index<60);
index≥60).
Median
follow-up
was
8.13
years.
Main
outcome
measures
The
primary
incident
(myocardial
infarction,
ischaemic
stroke)
or
death.
Results
Of
participants,
6.49%
(n=505
763)
had
T2DM.
More
T2DM
(34.06%)
(26.73%)
than
those
without
(grade
NAFLD:
21.20%;
10.02%).
incidence
rate
(per
1000
person
years)
increased
order
NAFLD,
rates
higher
five
year
absolute
(no
T2DM:
1.03,
95%
confidence
interval
1.02
to
1.04,
1.25,
1.24
1.26,
respectively;
1.23,
1.22
1.50,
1.48
1.51,
1.42,
1.40
1.45,
2.09,
2.06
2.12,
3.34,
3.27
3.41,
3.68,
3.61
3.74,
3.94,
3.87
4.02,
4.25,
4.18
4.33,
4.66,
4.54
4.78,
5.91,
5.78
6.05,
respectively).
Patients
a
NAFLD.
Risk
differences
between
Conclusions
seems
be
associated
death,
even
mild
group
Diabetes & Metabolism Journal,
Journal Year:
2025,
Volume and Issue:
49(1), P. 24 - 33
Published: Jan. 1, 2025
This
study
aimed
to
investigate
the
prevalence,
management,
and
comorbidities
of
diabetes
mellitus
among
Korean
adults.
Data
from
Korea
National
Health
Nutrition
Examination
Survey
(2019-2022)
were
analyzed
assess
treatment,
risk
factors,
diabetes.
Comparisons
between
young
older
adults
with
emphasized.
Among
aged
≥30
years,
prevalence
is
15.5%
during
2021-2022.
Of
these,
74.7%
aware
their
condition,
70.9%
received
antidiabetic
only
32.4%
achieved
glycosylated
hemoglobin
(HbA1c)
<6.5%.
Moreover,
15.9%
met
integrated
management
targets,
which
included
HbA1c
<6.5%,
blood
pressure
<140/85
mm
Hg,
low-density
lipoprotein
cholesterol
<100
mg/dL.
In
19
39
was
2.2%.
them,
43.3%
34.6%
29.6%
Obesity
affected
87.1%,
26.9%
had
both
hypertension
hypercholesterolemia.
≥65
29.3%,
awareness,
control
rates
78.8%,
75.7%,
31.2%,
respectively.
Integrated
targets
(HbA1c
<7.5%,
hypertension,
lipids)
by
40.1%.
Diabetes
remains
highly
prevalent
adults,
significant
gaps
in
glycemic,
pressure,
lipid
control.
Older
show
higher
awareness
treatment
but
limited
outcomes.
Young
bear
a
burden
obesity
comorbidities,
alongside
low
rates.
Therefore,
early
intervention
programs,
education,
strategies
tailored
younger
populations
are
urgently
required.
Diabetes & Metabolism Journal,
Journal Year:
2023,
Volume and Issue:
47(3), P. 347 - 355
Published: March 29, 2023
This
study
investigated
the
changes
of
fatty
liver
disease
prevalence
in
general
Korean
population.This
analyzed
data
from
National
Health
Insurance
Service
2009
to
2017
that
included
individuals
aged
20
years
or
older
who
had
undergone
a
medical
health
examination.
Fatty
was
assessed
using
index
(FLI).
The
severity
defined
by
FLI
cutoff,
≥30
as
moderate,
and
≥60
severe
disease.The
adults
over
with
(FLI
≥60)
increased
13.3%
15.5%
(P
for
trend
<0.001).
increase
prominent
men
(from
20.5%
24.2%)
young
age
(20
39
years)
group
12.8%
16.4%)
interaction
highest
type
2
diabetes
mellitus
(T2DM,
29.6%)
population
compared
prediabetes
normoglycemia
(10.0%
21.8%)
2017.
statistically
T2DM
Its
more
steeply
young-aged
T2DM,
42.2%
60.1%
When
applying
lower
cutoff
(≥30)
similar
results
were
observed.The
has
increased.
Individuals
are
young,
male,
have
vulnerable
disease.
Journal of Korean Medical Science,
Journal Year:
2024,
Volume and Issue:
39(7)
Published: Jan. 1, 2024
The
measurement
of
health
levels
and
monitoring
characteristics
trends
among
populations
subgroups
are
essential
for
informing
evidence-based
policy
decisions.
This
study
aimed
to
examine
the
burden
disease
in
Korea
both
total
population
2020,
as
well
analyze
changes
from
2008
2020.
Healthcare,
Journal Year:
2024,
Volume and Issue:
12(3), P. 368 - 368
Published: Jan. 31, 2024
There
has
been
increasing
interest
in
mobile
healthcare
for
diabetes
management.
However,
there
remains
limited
evidence
regarding
the
effectiveness
of
these
applications
(apps).
This
scoping
review
aimed
to
evaluate
clinical
management
apps.
We
used
following
search
terms:
“mobile
app”,
application”,
and
“diabetes”.
included
only
articles
written
English
published
between
January
2016
August
2021.
identified
two,
six,
four
focused
on
type
1
diabetes,
2
both
types,
respectively.
Five,
four,
three
studies
reported
apps’
functionality,
usability,
both,
Our
findings
indicated
that
apps
allowed
convenient
user
experience
improved
blood
sugar
levels
patients
with
diabetes.
Considering
findings,
usability
must
be
comprehensively
evaluated
by
using
definitions
such
as
ISO9241-11
definition
or
application
rating
scale
(MARS)
when
developing
diabetes-related
For
feasibility
apps,
we
recommend
HbA1C
self-management
evaluation
variables.
Given
importance
continuous
interventions
are
bound
become
effective
tools
patient-led
self-management.
Diabetes & Metabolism Journal,
Journal Year:
2025,
Volume and Issue:
49(1), P. 13 - 21
Published: Jan. 1, 2025
The
Korean
National
Health
Information
Database
(NHID),
which
contains
nationwide
real-world
claims
data
including
sociodemographic
data,
health
care
utilization
screening
and
healthcare
provider
information,
is
a
powerful
resource
to
test
various
hypotheses.
It
also
longitudinal
in
nature
due
the
recommended
checkup
every
2
years
appropriate
for
long-term
follow-up
study
as
well
evaluating
relationships
between
outcomes
changes
parameters
such
lifestyle
factors,
anthropometric
measurements,
laboratory
results.
However,
because
these
are
not
collected
research
purposes,
precise
operational
definitions
of
diseases
required
facilitate
big
analysis
using
NHID.
In
this
review,
we
describe
characteristics
NHID,
used
related
diabetes,
introduce
representative
diabetes-related
