Biomaterials Science,
Journal Year:
2020,
Volume and Issue:
9(1), P. 10 - 22
Published: May 22, 2020
Endowing
the
surfaces
of
synthetic
materials
with
bactericidal
activity
is
a
direct
and
effective
way
to
prevent
bacterial
colonization
biofilm
formation,
solving
related
serious
problems
such
as
contamination,
infection
biofouling.
Conventional
are
usually
based
on
biocidal
agents
antibiotics
kill
attached
bacteria;
however,
have
inherent
limitations
from
their
respective
most
them
become
less
against
so-called
"super
bacteria"
multidrug-resistance.
In
recent
years,
photothermal
promising
alternative
for
combating
surface-attached
bacteria.
These
rely
immobilized
agents,
which
can
convert
light
energy
into
thermal
effectively
eliminate
bacteria
through
various
hyperthermia
effects,
showing
several
advantages
including
broad-spectrum
sterilization
ability,
no
drug
resistance
few
side
effects.
this
review,
we
highlight
development
these
surfaces,
categorized
three
types
according
agents.
Multi-functional
either
integrated
synergistic
killing
mechanisms
or
capability
switch
function
between
releasing
also
introduced.
A
brief
perspective
finally
presented
directions
that
show
promise
future.
Chemical Reviews,
Journal Year:
2021,
Volume and Issue:
121(21), P. 13342 - 13453
Published: Sept. 27, 2021
Gold
nanorods
(NRs),
pseudo-one-dimensional
rod-shaped
nanoparticles
(NPs),
have
become
one
of
the
burgeoning
materials
in
recent
years
due
to
their
anisotropic
shape
and
adjustable
plasmonic
properties.
With
continuous
improvement
synthetic
methods,
a
variety
been
attached
around
Au
NRs
achieve
unexpected
or
improved
properties
explore
state-of-the-art
technologies.
In
this
review,
we
comprehensively
summarize
latest
progress
on
NRs,
most
versatile
NPs.
We
present
representative
overview
advances
strategies
outline
an
extensive
catalogue
Au-NR-based
heterostructures
with
tailored
architectures
special
functionalities.
The
bottom-up
assembly
into
preprogrammed
metastructures
is
then
discussed,
as
well
design
principles.
also
provide
systematic
elucidation
different
associated
structures,
followed
by
discussion
promising
applications
various
fields.
finally
discuss
future
research
directions
challenges
NRs.
Advanced Science,
Journal Year:
2021,
Volume and Issue:
8(19)
Published: Aug. 5, 2021
Healthcare-acquired
infections
as
well
increasing
antimicrobial
resistance
have
become
an
urgent
global
challenge,
thus
smart
alternative
solutions
are
needed
to
tackle
bacterial
infections.
Antibacterial
materials
in
biomedical
applications
and
hospital
hygiene
attracted
great
interest,
particular,
the
emergence
of
surface
design
strategies
offer
effective
antibiotics,
thereby
preventing
possible
development
resistance.
In
this
review,
recent
progress
on
advanced
modifications
prevent
addressed
comprehensively,
starting
with
key
factors
against
adhesion,
followed
by
varying
that
can
inhibit
biofilm
formation
effectively.
Furthermore,
"super
antibacterial
systems"
through
pre-treatment
defense
targeted
bactericidal
system,
proposed
evidence
clinical
potential.
Finally,
advantages
future
challenges
resist
healthcare-associated
discussed,
promising
prospects
developing
novel
materials.
Bioactive Materials,
Journal Year:
2023,
Volume and Issue:
30, P. 129 - 141
Published: July 28, 2023
In
clinical
applications,
there
is
a
lack
of
wound
dressings
that
combine
efficient
resistance
to
drug-resistant
bacteria
with
good
self-healing
properties.
this
study,
series
adhesive
conductive
antibacterial
hydrogel
based
on
oxidized
sodium
alginate-grafted
dopamine/carboxymethyl
chitosan/Fe3+
(OSD/CMC/Fe
hydrogel)/polydopamine-encapsulated
poly(thiophene-3-acetic
acid)
(OSD/CMC/Fe/PA
hydrogel)
were
prepared
for
the
repair
infected
wound.
The
Schiff
base
and
Fe3+
coordination
bonds
structure
are
dynamic
can
be
repaired
automatically
after
network
disrupted.
Macroscopically,
exhibits
properties,
allowing
dressing
adapt
complex
surfaces.
OSD/CMC/Fe/PA
showed
conductivity
photothermal
properties
under
near-infrared
(NIR)
light
irradiation.
addition,
hydrogels
exhibit
tunable
rheological
suitable
mechanical
antioxidant
tissue
adhesion
hemostatic
Furthermore,
all
improved
healing
in
full-thickness
defect
skin
test
mice.
size
by
OSD/CMC/Fe/PA3
+
NIR
was
much
smaller
(12%)
than
control
group
treated
Tegaderm™
film
14
days.
conclusion,
have
high
efficiency,
conductivity,
great
biocompatibility,
hemostasis
making
them
promising
candidates
treatment
wounds.
Bioactive Materials,
Journal Year:
2021,
Volume and Issue:
6(9), P. 2647 - 2657
Published: Feb. 15, 2021
Most
commonly
used
wound
dressings
have
severe
problems,
such
as
an
inability
to
adapt
shape
or
a
lack
of
antibacterial
capacity,
affecting
their
ability
meet
the
requirements
clinical
applications.
Here,
nanocomposite
hydrogel
(XKP)
is
developed
by
introducing
polydopamine
nanoparticles
(PDA
NPs)
into
food
gum
matrix
(XK,
consisting
xanthan
and
konjac
glucomannan,
both
FDA-approved
thickening
agents)
for
skin
healing.
In
this
system,
embedded
PDA
NPs
not
only
interact
with
form
excellent
mechanical
strength,
but
also
act
photothermal
transduction
agents
convert
near-infrared
laser
radiation
heat,
thereby
triggering
bacterial
death.
Moreover,
XKP
has
high
elasticity
tunable
water
content,
enabling
it
insulate
it,
providing
moist
environment
suitable
In-vivo
healing
results
clearly
demonstrate
that
can
significantly
accelerate
wounds
reducing
inflammatory
response
promoting
vascular
reconstruction.
summary,
strategy
provides
simple
practical
method
overcome
drawbacks
traditional
dressings,
further
options
when
choosing
materials
Cell Reports Physical Science,
Journal Year:
2020,
Volume and Issue:
1(11), P. 100245 - 100245
Published: Nov. 1, 2020
Recently,
photoactivated
sterilization,
as
a
rapid,
effective,
and
antibiotic-free
antibacterial
method,
has
attracted
increasing
attention
from
researchers.
Many
outstanding
photoresponsive
materials,
including
photocatalysts,
photosensitizers
(PSs),
photothermal
have
been
developed
applied
to
microbial
inactivation
treat
infectious
bacterial
diseases.
This
mini-review
aims
provide
insights
gathered
studying
materials
systems,
(1)
reactive
oxygen
species
(ROS)-based
photodynamic
therapy
(PDT)
(2)
hyperthermia-based
(PTT).
In
addition,
potential
application
fields
for
these
methods,
the
remaining
challenges
using
inactivation,
perspectives
future,
prospective
research
directions
are
discussed
in
depth.
