Nanocarbons for Biology and Medicine: Sensing, Imaging, and Drug Delivery DOI

Nishtha Panwar,

Alana Mauluidy Soehartono, Kok Ken Chan

et al.

Chemical Reviews, Journal Year: 2019, Volume and Issue: 119(16), P. 9559 - 9656

Published: July 9, 2019

Nanocarbons with different dimensions (e.g., 0D fullerenes and carbon nanodots, 1D nanotubes graphene nanoribbons, 2D oxides, 3D nanodiamonds) have attracted enormous interest for applications ranging from electronics, optoelectronics, photovoltaics to sensing, bioimaging, therapeutics due their unique physical chemical properties. Among them, nanocarbon-based theranostics (i.e., diagnostics) is one of the most intensively studied applications, as these nanocarbon materials serve excellent biosensors, versatile drug/gene carriers specific targeting in vivo, effective photothermal nanoagents cancer therapy, promising fluorescent nanolabels cell tissue imaging. This review provides a systematic overview latest theranostic comprehensive comparison characteristics influences on applications. We first introduce allotropes that can be used respective preparation surface functionalization approaches well Theranostic are described separately both vitro vivo systems by highlighting protocols biosystems, followed toxicity biodegradability implications. Finally, this outlines design considerations key unifying themes will foundational principle researchers study, investigate, generate effective, biocompatible, nontoxic materials-based models we summarize an outlook challenges novel using hard-to-treat cancers other diseases. intends present guideline nanotechnology biomedicine selection strategy according requirements.

Language: Английский

Near-infrared fluorophores for biomedical imaging DOI
Guosong Hong,

Alexander L. Antaris,

Hongjie Dai

et al.

Nature Biomedical Engineering, Journal Year: 2017, Volume and Issue: 1(1)

Published: Jan. 10, 2017

Language: Английский

Citations

2499
Reactive oxygen species generating systems meeting challenges of photodynamic cancer therapy DOI
Zijian Zhou, Jibin Song, Liming Nie

et al.

Chemical Society Reviews, Journal Year: 2016, Volume and Issue: 45(23), P. 6597 - 6626

Published: Jan. 1, 2016

Summary of advanced strategies to generate reactive oxygen species (ROS) through both photodynamic and non-photodynamic procedures for cancer therapy.

Language: Английский

Citations

1776
A small-molecule dye for NIR-II imaging DOI

Alexander L. Antaris,

Hao Chen, Kai Cheng

et al.

Nature Materials, Journal Year: 2015, Volume and Issue: 15(2), P. 235 - 242

Published: Nov. 23, 2015

Language: Английский

Citations

1532
Nanochemistry and Nanomedicine for Nanoparticle-based Diagnostics and Therapy DOI
Guanying Chen, Indrajit Roy, Chunhui Yang

et al.

Chemical Reviews, Journal Year: 2016, Volume and Issue: 116(5), P. 2826 - 2885

Published: Jan. 22, 2016

ADVERTISEMENT RETURN TO ISSUEPREVReviewNEXTNanochemistry and Nanomedicine for Nanoparticle-based Diagnostics TherapyGuanying Chen‡†, Indrajit Roy†§, Chunhui Yang*‡, Paras N. Prasad*†View Author Information† Institute Lasers, Photonics, Biophotonics Department of Chemistry, University at Buffalo, State New York, York 14260, United States‡ School Chemical Engineering Technology, Harbin Harbin, Heilongjiang 150001, China§ Delhi, Delhi 110007, India*E-mail: [email protected]*E-mail: protected]Cite this: Chem. Rev. 2016, 116, 5, 2826–2885Publication Date (Web):January 22, 2016Publication History Received12 March 2015Published online22 January 2016Published inissue 9 2016https://pubs.acs.org/doi/10.1021/acs.chemrev.5b00148https://doi.org/10.1021/acs.chemrev.5b00148review-articleACS PublicationsCopyright © 2016 American SocietyRequest reuse permissionsArticle Views28825Altmetric-Citations1183LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum full text article downloads since November 2008 (both PDF HTML) across all institutions individuals. These metrics regularly updated to reflect usage leading up last few days.Citations number other articles citing this article, calculated by Crossref daily. Find more information about citation counts.The Altmetric Attention Score is a quantitative measure attention that research has received online. Clicking on donut icon will load page altmetric.com with additional details score social media presence given article. how calculated. Share Add toView InAdd Full Text ReferenceAdd Description ExportRISCitationCitation abstractCitation referencesMore Options onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose SUBJECTS:Biological imaging,Fluorescence,Metal oxide nanoparticles,Nanoparticles,Quantum dots Get e-Alerts

Language: Английский

Citations

1351
Carbon Nanomaterials for Biological Imaging and Nanomedicinal Therapy DOI
Guosong Hong,

Shuo Diao,

Alexander L. Antaris

et al.

Chemical Reviews, Journal Year: 2015, Volume and Issue: 115(19), P. 10816 - 10906

Published: May 21, 2015

ADVERTISEMENT RETURN TO ISSUEPREVReviewNEXTCarbon Nanomaterials for Biological Imaging and Nanomedicinal TherapyGuosong Hong, Shuo Diao, Alexander L. Antaris, Hongjie Dai*View Author Information Department of Chemistry, Stanford University, Stanford, California 94305, United States*E-mail: [email protected]Cite this: Chem. Rev. 2015, 115, 19, 10816–10906Publication Date (Web):May 21, 2015Publication History Received5 January 2015Published online21 May inissue 14 October 2015https://pubs.acs.org/doi/10.1021/acs.chemrev.5b00008https://doi.org/10.1021/acs.chemrev.5b00008review-articleACS PublicationsCopyright © 2015 American Chemical SocietyRequest reuse permissionsArticle Views34513Altmetric-Citations1131LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum full text article downloads since November 2008 (both PDF HTML) across all institutions individuals. These metrics regularly updated to reflect usage leading up last few days.Citations number other articles citing this article, calculated by Crossref daily. Find more information about citation counts.The Altmetric Attention Score is a quantitative measure attention that research has received online. Clicking on donut icon will load page at altmetric.com with additional details score social media presence given article. how calculated. Share Add toView InAdd Full Text ReferenceAdd Description ExportRISCitationCitation abstractCitation referencesMore Options onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose SUBJECTS:Biological imaging,Carbon nanomaterials,Carbon nanotubes,Fluorescence,Fluorescence imaging Get e-Alerts

Language: Английский

Citations

1290
Clarifying Tissue Clearing DOI Creative Commons
Douglas S. Richardson, Jeff W. Lichtman

Cell, Journal Year: 2015, Volume and Issue: 162(2), P. 246 - 257

Published: July 1, 2015

Language: Английский

Citations

1049
Nanomaterials for In Vivo Imaging DOI
Bryan Ronain Smith, Sanjiv S. Gambhir

Chemical Reviews, Journal Year: 2017, Volume and Issue: 117(3), P. 901 - 986

Published: Jan. 3, 2017

In vivo imaging, which enables us to peer deeply within living subjects, is producing tremendous opportunities both for clinical diagnostics and as a research tool. Contrast material often required clearly visualize the functional architecture of physiological structures. Recent advances in nanomaterials are becoming pivotal generate high-resolution, high-contrast images needed accurate, precision diagnostics. Nanomaterials playing major roles imaging by delivering large payloads, yielding improved sensitivity, multiplexing capacity, modularity design. Indeed, several modalities, now not simply ancillary contrast entities, but instead original sole source image signal that make possible modality's existence. We address physicochemical makeup/design through lens physical properties produce cognate modality-we stratify on basis their (i) magnetic, (ii) optical, (iii) acoustic, and/or (iv) nuclear properties. evaluate them ability provide relevant information under preclinical circumstances, safety profiles (which being incorporated into chemical design), fused create multimodal (spanning multiple different modalities therapeutic/theranostic capabilities), key properties, critically likelihood be clinically translated.

Language: Английский

Citations

972
Crucial breakthrough of second near-infrared biological window fluorophores: design and synthesis toward multimodal imaging and theranostics DOI
Shuqing He, Jun Song, Junle Qu

et al.

Chemical Society Reviews, Journal Year: 2018, Volume and Issue: 47(12), P. 4258 - 4278

Published: Jan. 1, 2018

Recent advances in the chemical design and synthesis of fluorophores second near-infrared biological window (NIR-II) for multimodal imaging theranostics are summarized highlighted this review article.

Language: Английский

Citations

869
Near‐Infrared‐II Molecular Dyes for Cancer Imaging and Surgery DOI
Shoujun Zhu, Rui Tian,

Alexander L. Antaris

et al.

Advanced Materials, Journal Year: 2019, Volume and Issue: 31(24)

Published: April 26, 2019

Fluorescence bioimaging affords a vital tool for both researchers and surgeons to molecularly target variety of biological tissues processes. This review focuses on summarizing organic dyes emitting at transparency window termed the near-infrared-II (NIR-II) window, where minimal light interaction with surrounding allows photons travel nearly unperturbed throughout body. NIR-II fluorescence imaging overcomes penetration/contrast bottleneck in visible region, making it remarkable modality early diagnosis cancer highly sensitive tumor surgery. Due their convenient bioconjugation peptides/antibodies, molecular are desirable candidates targeted imaging, significantly overcoming autofluorescence/scattering issues deep tissue imaging. To promote clinical translation bioimaging, advancements high-performance small molecule-derived probes critically important. Here, molecules potential discussed, synthesis chemical structures dyes, optical properties behavior whole body detection surgery, as well microscopy A key perspective direction surgery is also discussed.

Language: Английский

Citations

814
Advanced Fluorescence Imaging Technology in the Near-Infrared-II Window for Biomedical Applications DOI
Chunyan Li, Guangcun Chen, Yejun Zhang

et al.

Journal of the American Chemical Society, Journal Year: 2020, Volume and Issue: 142(35), P. 14789 - 14804

Published: Aug. 7, 2020

Fluorescence imaging has become a fundamental tool for biomedical applications; nevertheless, its intravital capacity in the conventional wavelength range (400–950 nm) been restricted by extremely limited tissue penetration. To tackle this challenge, novel approach using fluorescence second near-infrared window (NIR-II, 1000–1700 developed past decade to achieve deep penetration and high-fidelity imaging, thus significant applications have begun emerge. In Perspective, we first examine recent discoveries challenges development of NIR-II fluorophores compatible apparatuses. Subsequently, advances bioimaging, biosensing, therapy such cutting-edge technique are highlighted. Finally, based on achievement representative studies, elucidate main concerns regarding give some advice prospects future applications.

Language: Английский

Citations

778