Pharmaceutics,
Journal Year:
2022,
Volume and Issue:
14(5), P. 937 - 937
Published: April 26, 2022
Cancer
is
among
the
leading
causes
of
mortality
globally,
with
nearly
10
million
deaths
in
2020.
The
emergence
nanotechnology
has
revolutionised
treatment
strategies
medicine,
rigorous
research
focusing
on
designing
multi-functional
nanoparticles
(NPs)
that
are
biocompatible,
non-toxic,
and
target-specific.
Iron-oxide-based
NPs
have
been
successfully
employed
theranostics
as
imaging
agents
drug
delivery
vehicles
for
anti-cancer
treatment.
Substituted
iron-oxides
(MFe2O4)
emerged
potential
nanocarriers
due
to
their
unique
attractive
properties
such
size
magnetic
tunability,
ease
synthesis,
manipulatable
properties.
Current
explores
use
hyperthermia
cancer
therapy.
Significantly,
there
considerations
applying
iron-oxide-based
enhanced
biocompatibility,
biodegradability,
colloidal
stability,
lowered
toxicity,
more
efficient
targeted
delivery.
This
review
covers
therapy,
recent
advances
ferrites.
Methods
synthesis
cubic
spinel
ferrites
requirements
therapy
discussed.
highlights
surface
modifications,
where
functionalisation
specific
biomolecules
can
deliver
better
efficiency.
Finally,
challenges
solutions
summarised.
Biomolecules,
Journal Year:
2020,
Volume and Issue:
10(10), P. 1429 - 1429
Published: Oct. 9, 2020
Glutathione
(GSH)
is
the
most
abundant
non-protein
thiol
present
at
millimolar
concentrations
in
mammalian
tissues.
As
an
important
intracellular
antioxidant,
it
acts
as
a
regulator
of
cellular
redox
state
protecting
cells
from
damage
caused
by
lipid
peroxides,
reactive
oxygen
and
nitrogen
species,
xenobiotics.
Recent
studies
have
highlighted
importance
GSH
key
signal
transduction
reactions
controller
cell
differentiation,
proliferation,
apoptosis,
ferroptosis
immune
function.
Molecular
changes
antioxidant
system
disturbances
homeostasis
been
implicated
tumor
initiation,
progression,
treatment
response.
Hence,
has
both
protective
pathogenic
roles.
Although
healthy
crucial
for
removal
detoxification
carcinogens,
elevated
levels
are
associated
with
progression
increased
resistance
to
chemotherapeutic
drugs.
Recently,
several
novel
therapies
developed
target
tumors
means
response
decreased
drug
resistance.
In
this
comprehensive
review
we
explore
mechanisms
functionalities
different
therapeutic
approaches
that
either
directly,
indirectly
or
use
GSH-based
prodrugs.
Consideration
also
given
computational
methods
used
describe
related
processes
silico
testing
effects.
Nanomaterials,
Journal Year:
2022,
Volume and Issue:
12(3), P. 457 - 457
Published: Jan. 28, 2022
In
the
last
few
decades,
vast
potential
of
nanomaterials
for
biomedical
and
healthcare
applications
has
been
extensively
investigated.
Several
case
studies
demonstrated
that
can
offer
solutions
to
current
challenges
raw
materials
in
fields.
This
review
describes
different
nanoparticles
nanostructured
material
synthesis
approaches
presents
some
emerging
biomedical,
healthcare,
agro-food
applications.
focuses
on
various
nanomaterial
types
(e.g.,
spherical,
nanorods,
nanotubes,
nanosheets,
nanofibers,
core-shell,
mesoporous)
be
synthesized
from
their
bioimaging,
biosensing,
drug
delivery,
tissue
engineering,
antimicrobial,
agro-foods.
Depending
morphology
size,
aspect
ratio,
geometry,
porosity),
used
as
formulation
modifiers,
moisturizers,
nanofillers,
additives,
membranes,
films.
As
toxicological
assessment
depends
sizes
morphologies,
stringent
regulation
is
needed
testing
efficient
dosages.
The
perspectives
an
industrial
breakthrough
are
related
optimization
production
processing
conditions.
Nanomaterials,
Journal Year:
2022,
Volume and Issue:
12(2), P. 177 - 177
Published: Jan. 6, 2022
Nanomaterials
are
becoming
important
materials
in
several
fields
and
industries
thanks
to
their
very
reduced
size
shape-related
features.
Scientists
think
that
nanoparticles
nanostructured
originated
during
the
Big
Bang
process
from
meteorites
leading
formation
of
universe
Earth.
Since
1990,
term
nanotechnology
became
popular
due
advances
imaging
technologies
paved
way
specific
industrial
applications.
Currently,
synthesized
on
a
large
scale
indispensable
for
many
industries.
This
fact
fosters
supports
research
biochemistry,
biophysics,
biochemical
engineering
Recently,
has
been
combined
with
other
sciences
fabricate
new
forms
nanomaterials
could
be
used,
instance,
diagnostic
tools,
drug
delivery
systems,
energy
generation/storage,
environmental
remediation
as
well
agriculture
food
processing.
In
contrast
traditional
materials,
features
can
integrated
into
nanoparticles,
nanostructures,
nanosystems
by
simply
modifying
scale,
shape,
composition.
article
first
summarizes
history
nanotechnology.
Followed
progress
led
improved
synthesis
processes
produce
different
nanostructures
characterized
The
content
finally
presents
various
origins
sources
nanomaterials,
strategies,
toxicity,
risks,
regulations,
self-aggregation.
Nanomaterials,
Journal Year:
2023,
Volume and Issue:
13(3), P. 574 - 574
Published: Jan. 31, 2023
The
human
nature
of
curiosity,
wonder,
and
ingenuity
date
back
to
the
age
humankind.
In
parallel
with
our
history
civilization,
interest
in
scientific
approaches
unravel
mechanisms
underlying
natural
phenomena
has
been
developing.
Recent
years
have
witnessed
unprecedented
growth
research
area
pharmaceuticals
medicine.
optimism
that
nanotechnology
(NT)
applied
medicine
drugs
is
taking
serious
steps
bring
about
significant
advances
diagnosing,
treating,
preventing
disease-a
shift
from
fantasy
reality.
growing
future
medical
applications
NT
leads
emergence
a
new
field
for
nanomaterials
(NMs)
biomedicine.
recent
years,
NMs
emerged
as
essential
game
players
modern
medicine,
clinical
ranging
contrast
agents
imaging
carriers
drug
gene
delivery
into
tumors.
Indeed,
there
are
instances
where
nanoparticles
(NPs)
enable
analyses
therapies
cannot
be
performed
otherwise.
However,
NPs
also
unique
environmental
societal
challenges,
particularly
concerning
toxicity.
Thus,
should
revisited,
deep
understanding
effects
pathophysiologic
basis
disease
may
more
sophisticated
diagnostic
opportunities
yield
effective
preventive
features.
Correspondingly,
this
review
highlights
contributions
systems.
This
study
attempted
glimpse
impact
pharmaceuticals.
Materials,
Journal Year:
2021,
Volume and Issue:
14(20), P. 5978 - 5978
Published: Oct. 11, 2021
Carbon
nanomaterials
(CNMs)
have
received
tremendous
interest
in
the
area
of
nanotechnology
due
to
their
unique
properties
and
flexible
dimensional
structure.
CNMs
excellent
electrical,
thermal,
optical
that
make
them
promising
materials
for
drug
delivery,
bioimaging,
biosensing,
tissue
engineering
applications.
Currently,
there
are
many
types
CNMs,
such
as
quantum
dots,
nanotubes,
nanosheets,
nanoribbons;
others
development
promise
exciting
applications
future.
The
surface
functionalization
modifies
chemical
physical
properties,
which
enhances
loading/release
capacity,
ability
target
delivery
specific
sites,
dispersibility
suitability
biological
systems.
Thus,
been
effectively
used
different
biomedical
This
review
explores
physical,
chemical,
allow
improve
on
state
art
currently
discussion
also
embraces
emerging
including
targeted
medical
implants,
engineering,
wound
healing,
vaccination,
photodynamic
therapy.
Nano Convergence,
Journal Year:
2020,
Volume and Issue:
7(1)
Published: Nov. 16, 2020
Abstract
Water
is
a
significant
natural
resource
for
humans.
As
such,
wastewater
containing
heavy
metals
seen
as
grave
problem
the
environment.
Currently,
adsorption
one
of
common
methods
used
both
water
purification
and
treatment.
Adsorption
relies
on
physical
chemical
interactions
between
metal
ions
adsorbents.
Adsorptive
membranes
(AMs)
have
demonstrated
high
effectiveness
in
removal
from
owing
to
their
exclusive
structural
properties.
This
article
examines
applications
adsorptive
such
polymeric
(PMs),
polymer-ceramic
(PCMs),
electrospinning
nanofiber
(ENMs),
nano-enhanced
(NEMs),
which
demonstrate
selectivity
capacity
ions,
well
advantages
disadvantages
each
all,
are
summarized
compared
shortly.
Moreover,
general
theories
isotherms
kinetics
described
briefly
comprehend
process.
work
will
be
valuable
readers
understanding
current
various
AMs
mechanisms
ion
adsorption,
recycling
desorption
process
clearly.
Besides,
influences
morphological
structures
presented
detail
well.
Nano Convergence,
Journal Year:
2021,
Volume and Issue:
8(1)
Published: Nov. 2, 2021
Modern
medicine
has
been
waging
a
war
on
cancer
for
nearly
century
with
no
tangible
end
in
sight.
Cancer
treatments
have
significantly
progressed,
but
the
need
to
increase
specificity
and
decrease
systemic
toxicities
remains.
Early
diagnosis
holds
key
improving
prognostic
outlook
patient
quality
of
life,
diagnostic
tools
are
cusp
technological
revolution.
Nanotechnology
steadily
expanded
into
reaches
chemotherapy,
radiotherapy,
diagnostics,
imaging,
demonstrating
capacity
augment
each
advance
care.
Nanomaterials
provide
an
abundance
versatility,
functionality,
applications
engineer
specifically
targeted
medicine,
accurate
early-detection
devices,
robust
imaging
modalities,
enhanced
radiotherapy
adjuvants.
This
review
provides
insights
current
clinical
pre-clinical
nanotechnological
drug
therapy,
radiation
therapy.
Biomolecules,
Journal Year:
2021,
Volume and Issue:
11(4), P. 564 - 564
Published: April 12, 2021
Plants
are
rich
in
phytoconstituent
biomolecules
that
served
as
a
good
source
of
medicine.
More
recently,
they
have
been
employed
synthesizing
metal/metal
oxide
nanoparticles
(NPs)
due
to
their
capping
and
reducing
properties.
This
green
synthesis
approach
is
environmentally
friendly
allows
the
production
desired
NPs
different
sizes
shapes
by
manipulating
parameters
during
process.
The
most
commonly
used
metals
oxides
gold
(Au),
silver
(Ag),
copper
(Cu).
Among
these,
Cu
relatively
low-cost
metal
more
cost-effective
than
Au
Ag.
In
this
review,
we
present
an
overview
current
update
plant-mediated
Cu/copper
(CuO)
NPs,
including
synthesis,
medicinal
applications,
mechanisms.
Furthermore,
toxic
effects
these
efficacy
compared
commercial
reviewed.
review
provides
insight
into
potential
developing
plant-based
Cu/CuO
therapeutic
agent
for
various
diseases
future.
