Advanced Science,
Journal Year:
2025,
Volume and Issue:
unknown
Published: Jan. 3, 2025
Abstract
Periodic
table
of
chemical
elements
serves
as
the
foundation
material
chemistry,
impacting
human
health
in
many
different
ways.
It
contributes
to
creation,
growth,
and
manipulation
functional
metallic,
ceramic,
metalloid,
polymeric,
carbon‐based
materials
on
near
an
atomic
scale.
Recent
nanotechnology
advancements
have
revolutionized
field
biomedical
engineering
tackle
longstanding
clinical
challenges.
The
use
nano‐biomaterials
has
gained
traction
medicine,
specifically
areas
nano‐immunoengineering
treat
inflammatory
infectious
diseases.
Two‐dimensional
(2D)
nanomaterials
been
found
possess
high
bioactive
surface
area
compatibility
with
mammalian
cells
at
controlled
doses.
Furthermore,
these
biomaterials
intrinsic
immunomodulatory
properties,
which
is
crucial
for
their
application
immuno‐nanomedicine.
While
significant
progress
made
understanding
bioactivity
biocompatibility,
exact
responses
mechanisms
are
still
being
explored.
Current
work
outlines
innovative
“immunomodulatory
periodic
elements”
beyond
life,
microbial
genomics
comprehensively
reviews
role
each
element
designing
immunoengineered
2D
a
group‐wise
manner.
recapitulates
most
recent
advances
nanomaterials,
paving
way
development
new
mono,
hybrid,
composite,
hetero‐structured
biomaterials.
Nature Communications,
Journal Year:
2024,
Volume and Issue:
15(1)
Published: March 21, 2024
Abstract
Photodynamic
therapy
(PDT)
is
a
promising
cancer
treatment
but
has
limitations
due
to
its
dependence
on
oxygen
and
high-power-density
photoexcitation.
Here,
we
report
polymer-based
organic
photosensitizers
(PSs)
through
rational
PS
skeleton
design
precise
side-chain
engineering
generate
•O
2
−
•OH
under
oxygen-free
conditions
using
ultralow-power
808
nm
photoexcitation
for
tumor-specific
photodynamic
ablation.
The
designed
skeletons
can
electron-hole
pairs
sensitize
H
O
into
with
photoexcitation,
achieving
NIR-photoexcited
oxygen-independent
production.
Further,
compared
commonly
used
alkyl
side
chains,
glycol
oligomer
as
the
chain
mitigates
recombination
offers
more
molecules
around
generated
from
hydrophobic
skeletons,
which
yield
4-fold
stronger
production,
thus
allowing
an
high
PDT
effect.
Finally,
feasibility
of
developing
activatable
PSs
in
female
mice
further
demonstrated
irradiation
15
mW
cm
−2
.
study
not
only
provides
insights
mechanism
also
general
guideline
develop
NIR
PDT.
EcoEnergy,
Journal Year:
2023,
Volume and Issue:
1(2), P. 248 - 295
Published: Dec. 1, 2023
Abstract
In
the
advancing
world
of
graphene,
highly
anisotropic
2D
semiconductor
nanosheets,
notable
for
their
nanometer‐scale
thickness,
have
emerged
as
a
leading
innovation,
displaying
immense
potential
in
exploration
renewable
and
clean
energy
production.
These
garnered
significant
attention
from
researchers.
The
nanosheets
are
marked
by
extraordinary
electronic,
optical,
chemical
attributes,
positioning
them
attractive
foundational
components
heterogeneous
photocatalysts.
This
review
diligently
summarizes
both
seminal
work
ongoing
developments
pertaining
to
application
solar
within
context
photocatalysis.
We
begin
detailing
distinctive
properties
concentrating
on
pivotal
roles
augmenting
photocatalytic
efficiency,
explaining
intrinsic
mechanisms
that
govern
migration
rate
photogenerated
carriers
material's
surface.
Subsequently,
we
delineate
methods
employed
synthesize
typical
nanosheets.
alignment
with
overarching
objective
expanding
light
absorption
capacity
accelerating
charge
transfer,
also
examine
current
research
hybridization
techniques
involving
materials
varied
dimensions,
well
deployment
diverse
applications.
conclude
identifying
promising
avenues
challenges
await
further
this
burgeoning
field.
Advanced Materials,
Journal Year:
2024,
Volume and Issue:
36(23)
Published: Feb. 27, 2024
Abstract
Although
metal
single‐atom
(SA)‐based
nanomaterials
are
explored
as
sonosensitizers
for
sonodynamic
therapy
(SDT),
they
normally
exhibit
poor
activities
and
need
to
combine
with
other
therapeutic
strategies.
Herein,
the
deposition
of
SAs
on
oxygen
vacancy
(OV)‐rich
WO
3−
x
nanosheets
generate
a
synergistic
effect
efficient
SDT
is
reported.
Crystalline
3
OV‐rich
first
prepared
by
simple
calcination
·H
2
O
under
an
air
N
atmosphere,
respectively.
Pt,
Cu,
Fe,
Co,
Ni
then
deposited
obtain
SA‐decorated
nanocomposites
(M‐WO
).
Importantly,
Cu‐WO
sonosensitizer
exhibits
much
higher
activity
ultrasound
(US)‐induced
production
reactive
species
than
that
Cu
,
which
also
M‐WO
nanosheets.
Both
experimental
theoretical
results
suggest
excellent
performance
should
be
attributed
between
OVs.
Therefore,
after
polyethylene
glycol
modification,
can
quickly
kill
cancer
cells
in
vitro
effectively
eradicate
tumors
vivo
US
irradiation.
Transcriptome
sequencing
analysis
further
molecular
validation
‐mediated
SDT‐activated
apoptosis
TNF
signaling
pathways
potential
drivers
tumor
induction.
Advanced Healthcare Materials,
Journal Year:
2023,
Volume and Issue:
12(31)
Published: Sept. 14, 2023
Abstract
Although
CeO
2
nanomaterials
have
been
widely
explored
as
nanozymes
for
catalytic
therapy,
they
still
suffer
from
relatively
low
activities.
Herein,
the
catalyzing
generation
and
stabilization
of
oxygen
vacancies
on
nanorods
by
Pt
nanoclusters
via
H
gas
reduction
under
mild
temperature
(350
°C)
to
obtain
Pt/CeO
2−
x
,
which
can
serve
a
highly
efficient
nanozyme
cancer
is
reported.
The
deposited
atomic
layer
deposition
technique
not
only
catalyst
generate
through
hydrogen
spillover
effect,
but
also
stabilize
generated
vacancies.
Meanwhile,
provide
anchoring
sites
forming
strong
metal‐support
interactions
thus
preventing
their
agglomerations.
Importantly,
reduced
at
350
°C
(Pt/CeO
‐350R)
exhibits
excellent
enzyme‐mimicking
activity
reactive
species
(e.g.,
·OH)
compared
other
control
samples,
including
temperatures,
achieving
performance
tumor‐specific
therapy
efficiently
eliminate
cells
in
vitro
ablate
tumors
vivo.
‐350R
originates
good
activities
vacancy‐rich
nanoclusters.
Advanced Materials,
Journal Year:
2024,
Volume and Issue:
36(15)
Published: Jan. 17, 2024
Abstract
Nanotechnology
profoundly
affects
the
advancement
of
medicine.
Limitations
in
diagnosing
and
treating
cancer
chronic
diseases
promote
growth
nanomedicine.
However,
there
are
very
few
analytical
descriptive
studies
regarding
trajectory
nanomedicine,
key
research
powers,
present
landscape,
focal
investigative
points,
future
outlooks.
Herein,
articles
reviews
published
Science
Citation
Index
Expanded
Web
Core
Collection
from
first
January
2000
to
18th
July
2023
analyzed.
a
bibliometric
visualization
publication
trends,
countries/regions,
institutions,
journals,
categories,
themes,
references,
keywords
is
produced
elaborated.
Nanomedicine‐related
academic
output
increasing
since
COVID‐19
pandemic,
solidifying
uneven
global
distribution
performance.
While
China
leads
terms
quantity
has
numerous
highly
productive
USA
advantages
impact,
commercialization,
industrial
value.
Nanomedicine
integrates
with
other
disciplines,
establishing
interdisciplinary
platforms,
which
drug
delivery
nanoparticles
remain
points.
Current
focuses
on
integrating
nanomedicine
cell
ferroptosis
induction
immunotherapy.
The
keyword
“burst
testing”
identifies
promising
directions,
including
immunogenic
death,
chemodynamic
therapy,
tumor
microenvironment,
immunotherapy,
extracellular
vesicles.
prospects,
major
challenges,
barriers
addressing
these
directions
discussed.
Advanced Science,
Journal Year:
2024,
Volume and Issue:
11(20)
Published: March 19, 2024
Abstract
Layered
double
hydroxides
(LDHs)
have
been
widely
studied
for
biomedical
applications
due
to
their
excellent
properties,
such
as
good
biocompatibility,
degradability,
interlayer
ion
exchangeability,
high
loading
capacity,
pH‐responsive
release,
and
large
specific
surface
area.
Furthermore,
the
flexibility
in
structural
composition
ease
of
modification
LDHs
makes
it
possible
develop
specifically
functionalized
meet
needs
different
applications.
In
this
review,
recent
advances
applications,
which
include
LDH‐based
drug
delivery
systems,
cancer
diagnosis
therapy,
tissue
engineering,
coatings,
functional
membranes,
biosensors,
are
comprehensively
discussed.
From
these
various
research
fields,
can
be
seen
that
there
is
great
potential
possibility
use
However,
at
same
time,
must
recognized
actual
clinical
translation
still
very
limited.
Therefore,
current
limitations
related
on
discussed
by
combining
limited
examples
with
requirements
biomaterials.
Finally,
an
outlook
future
provided.
