Oxygen,
Journal Year:
2024,
Volume and Issue:
4(1), P. 1 - 19
Published: Jan. 22, 2024
A
member
of
the
Verbenaceae
family,
Aloysia
citrodora,
or
lemon
verbena,
is
a
medicinal
herb
with
antioxidant
compounds.
The
aim
this
study
was
to
develop
green,
optimized
method
for
bioactive
compound
(carotenoids,
ascorbic
acid,
and
polyphenols)
extraction
from
verbena
leaves
through
response
surface
methodology
(RSM).
recovery
shown
be
significantly
affected
by
technique
(both
pulsed
electric
field
ultrasound-assisted
extraction),
along
an
solvent,
based
on
partial
least
squares
analysis.
Consequently,
maximum
polyphenol
yield
required
double-assisted
relatively
low
duration
(60
min)
at
high
temperature
(80
°C),
moderate-polarity
solvent
(50%
v/v
ethanol).
With
method,
total
content
(TPC)
measured
175.03
mg
gallic
acid
equivalents/g,
whereas
chromatographic
analysis
revealed
that
verbascoside
most
prevalent
(132.61
mg/g).
optimum
extract
provided
capacity
measurements
FRAP
(1462.17
μmol
equivalents
(AAE)/g),
DPPH
(1108.91
AAE/g),
H2O2
(1662.93
AAE/g).
Total
carotenoids
were
499.61
μg/g,
8.36
μg/g.
Correlation
analyses
negative
correlation
latter
color
coordinates.
This
highlights
potential
used
in
pharmaceutical
food
industries.
Foods,
Journal Year:
2020,
Volume and Issue:
9(4), P. 534 - 534
Published: April 24, 2020
Nature
has
generously
offered
a
wide
range
of
herbs
(e.g.,
thyme,
oregano,
rosemary,
sage,
mint,
basil)
rich
in
many
polyphenols
and
other
phenolic
compounds
with
strong
antioxidant
biochemical
properties.
This
paper
focuses
on
several
natural
occurring
acids
(caffeic,
carnosic,
ferulic,
gallic,
p-coumaric,
rosmarinic,
vanillic)
first
gives
an
overview
their
most
common
plant
sources.
A
summary
the
recently
reported
activities
o/w
emulsions
is
also
provided
as
vitro
lipid-based
model
system.
Exploring
interfacial
activity
could
help
to
further
elucidate
potential
health
properties
against
oxidative
stress
conditions
biological
membranes
(such
lipoproteins).
Finally,
this
review
reports
latest
literature
evidence
concerning
specific
examined
acids.
European Journal of Nutrition,
Journal Year:
2019,
Volume and Issue:
59(4), P. 1275 - 1293
Published: May 21, 2019
Phenolic
acids
are
important
phenolic
compounds
widespread
in
foods,
contributing
to
nutritional
and
organoleptic
properties.
The
bioavailability
of
these
depends
on
their
free
or
conjugated
presence
food
matrices,
which
is
also
affected
by
processing.
undergo
metabolism
the
host
residing
intestinal
microbiota,
causes
conjugations
structural
modifications
compounds.
Human
responses,
metabolite
profiles
health
responses
phenolics,
show
considerable
individual
variation,
absorption,
genetic
variations
subjects.
A
better
understanding
gut-host
interplay
microbiome
biochemistry
becoming
highly
relevant
impact
diet
its
constituents.
It
common
study
benefits
separately,
with
some
exceptions;
however,
it
should
be
preferred
that
responders
non-responders
studied
combination
explanatory
gene
variants.
This
approach
could
turn
interindividual
variation
from
a
problem
human
research
an
asset
for
personalized
nutrition.
Antioxidants,
Journal Year:
2021,
Volume and Issue:
10(7), P. 1129 - 1129
Published: July 15, 2021
Arbutin
is
a
compound
of
hydroquinone
and
D-glucose,
it
has
been
over
30
years
since
there
have
serious
studies
on
the
skin
lightening
action
this
substance.
In
meantime,
debates
validation
about
mechanism
substance
as
well
its
efficacy
safety.
Several
analogs
or
derivatives
arbutin
developed
studied
for
their
melanin
synthesis
inhibitory
action.
Formulations
to
improve
stability,
transdermal
delivery,
release
arbutin,
device
usage
promote
absorption
developed.
Substances
that
inhibit
synergistically
with
explored.
The
alone
in
combination
other
active
ingredients
clinically
evaluated.
Combined
therapy
laser
could
give
enhanced
depigmenting
efficacy.
use
causes
dermatitis
rarely,
caution
recommended
arbutin-containing
products,
especially
from
viewpoint
may
be
generated
during
product
use.
Studies
antioxidant
properties
are
emerging,
these
proposed
contribute
arbutin.
It
hoped
review
will
help
understand
pros
cons
cosmetic
ingredient,
lead
future
research
directions
developing
advanced
protecting
products.
Antioxidants,
Journal Year:
2021,
Volume and Issue:
10(8), P. 1315 - 1315
Published: Aug. 21, 2021
Vitamin
B3
(nicotinic
acid,
niacin)
deficiency
causes
the
systemic
disease
pellagra,
which
leads
to
dermatitis,
diarrhea,
dementia,
and
possibly
death
depending
on
its
severity
duration.
is
used
in
synthesis
of
NAD
Small,
Journal Year:
2023,
Volume and Issue:
19(19)
Published: Feb. 9, 2023
Oral
antioxidant
nanozymes
bring
great
promise
for
inflammatory
bowel
disease
(IBD)
treatment.
To
efficiently
eliminate
reactive
oxygen
species
(ROS),
various
metal-based
have
been
developed
the
treatment
of
IBD
but
their
practical
applications
are
seriously
impaired
by
unstable
ROS-eliminating
properties
and
potential
metal
ion
leakage
in
digestive
tract.
Here,
authors
first
time
propose
metal-free
melanin
(MeNPs)
with
excellent
gastrointestinal
stability
biocompatibility
as
a
favorable
therapy
strategy
IBD.
Moreover,
MeNPs
extremely
natural
long-lasting
characteristics
targeting
lesions.
In
view
dominant
role
ROS
IBD,
further
reveal
that
oral
administration
can
greatly
alleviate
six
major
pathological
features
IBD:
oxidative
stress,
endoplasmic
reticulum
apoptosis,
inflammation,
gut
barrier
disruption,
dysbiosis.
Overall,
this
highlights
clinical
application
prospects
via
harnessing
scavenging
at
lesions,
offering
paradigm
nanozyme
or
other
diseases.
Antioxidants,
Journal Year:
2024,
Volume and Issue:
13(4), P. 429 - 429
Published: March 30, 2024
Polyphenols,
as
secondary
metabolites
ubiquitous
in
plant
sources,
have
emerged
pivotal
bioactive
compounds
with
far-reaching
implications
for
human
health.
Plant
polyphenols
exhibit
direct
or
indirect
associations
biomolecules
capable
of
modulating
diverse
physiological
pathways.
Due
to
their
inherent
abundance
and
structural
diversity,
garnered
substantial
attention
from
both
the
scientific
clinical
communities.
The
review
begins
by
providing
an
in-depth
analysis
chemical
intricacies
polyphenols,
shedding
light
on
diversity
such
biological
activities.
Subsequently,
exploration
dietary
origins
elucidates
natural
plant-based
sources
that
contribute
global
availability.
discussion
extends
bioavailability
metabolism
within
body,
unraveling
complex
journey
ingestion
systemic
effects.
A
central
focus
is
dedicated
unravelling
antioxidant
effects
highlighting
role
combating
oxidative
stress
associated
health
conditions.
comprehensive
encompasses
impact
concerns
hypertension,
allergies,
aging,
chronic
diseases
like
heart
stroke
diabetes.
Insights
into
beneficial
further
underscore
potential
preventive
therapeutic
agents.
This
article
critically
examines
multifaceted
aspects
encompassing
chemistry,
origins,
bioavailability/metabolism
dynamics,
profound
synthesis
information
presented
herein
aims
provide
a
valuable
resource
researchers,
clinicians,
enthusiasts,
fostering
deeper
understanding
intricate
relationship
between
Cancers,
Journal Year:
2024,
Volume and Issue:
16(12), P. 2262 - 2262
Published: June 18, 2024
Melanoma,
originating
through
malignant
transformation
of
melanin-producing
melanocytes,
is
a
formidable
malignancy,
characterized
by
local
invasiveness,
recurrence,
early
metastasis,
resistance
to
therapy,
and
high
mortality
rate.
This
review
discusses
etiologic
risk
factors
for
melanoma,
diagnostic
prognostic
tools,
including
recent
advances
in
molecular
biology,
omics,
bioinformatics,
provides
an
overview
its
therapy.
Since
the
incidence
melanoma
rising
remains
unacceptably
high,
we
discuss
inherent
properties,
melanogenesis,
that
make
this
disease
resilient
treatment
propose
use
AI
solve
above
complex
multidimensional
problems.
We
provide
on
vitamin
D
anticancerogenic
report
field
can
solutions
prevention
and/or
therapy
melanoma.
Experimental
papers
clinicopathological
studies
role
status
signaling
pathways
initiated
active
metabolites
prognosis
are
reviewed.
conclude
signaling,
defined
specific
nuclear
receptors
selective
activation
hydroxyderivatives,
benefit
new
or
existing
therapeutic
approaches.
target
with
computational
biology
tools
solution
problem.
