Journal of Aquatic Food Product Technology,
Journal Year:
2023,
Volume and Issue:
32(2), P. 158 - 174
Published: Feb. 7, 2023
The
exploration
of
bioactive
phytochemical
quantities
two
underutilized
Sri
Lankan
seaweeds
Ulva
lactuca
(UL)
and
fasciata
(UF)
revealed
significant
phenolic,
flavonoid,
ulvan,
carotenoid,
chlorophyll,
tannin,
saponin,
alkaloid
contents,
DPPH
radical
scavenging
activities.
To
evaluate
their
application
in
developing
seaweed
incorporated
cereal-based
functional
snacks,
wheat
crackers
were
formulated
using
0%
(control),
2%,
4%
powder
as
a
flour
replacement.
Developed
had
elevated
sensory
acceptability,
protein,
ash
contents
activities,
confirming
the
capacity
UL
UF
utilization
producing
potentially
snacks
with
improved
nutritional
attributes.
Plants,
Journal Year:
2025,
Volume and Issue:
14(3), P. 352 - 352
Published: Jan. 24, 2025
Fumaria
officinalis
(fumitory),
in
the
form
of
dust,
was
employed
as
a
source
bioactive
extracts
whose
chemical
profile
and
biological
potential
were
investigated.
According
to
results
optimization
extraction
protocol,
extract
with
highest
polyphenol
yield
prepared
using
fumitory
dust
under
optimal
conditions
determined
statistical
tool,
23
full
factorial
design:
50%
ethanol
30:1
mL/g
ratio
during
120
s
microwave
(22.56
mg
gallic
acid
equivalent/g
plant
material).
LC-MS
spectrophotometric/gravimetric
analyses
quantified
polyphenol,
flavonoid,
tannin,
alkaloid,
protein
contents.
Caffeoylmalic
acid,
quercetin
dihexoside,
pentoside
hexoside,
rutin,
methylquercetin
dihexoside
most
dominant
compounds.
The
total
condensed
yields
microwaves.
In
addition
proven
antioxidant
potential,
present
study,
anti-inflammatory
activity
is
also
keratinocyte
model,
well
significant
reduction
H2O2-induced
reactive
oxygen
species
production
cells
absence
cytotoxicity.
Thus,
detailed
profiles
investigated
effects
related
skin
health
benefits
encourage
application
dermo-cosmetic
pharmaceutical
preparations
for
dermatological
circumstances.
Oxidative Medicine and Cellular Longevity,
Journal Year:
2025,
Volume and Issue:
2025(1)
Published: Jan. 1, 2025
This
study
intends
to
investigate
the
green
synthesis
of
silver
(Ag)
and
gold
(Au)
nanoparticles
(NPs)
using
Echinophora
platyloba
extract
evaluate
antioxidant
anti‐inflammatory
effects
synthesized
NPs
extract.
In
this
study,
aqueous
hydroalcoholic
extracts
E.
were
prepared,
which
used
for
biosynthesis
Ag
Au
NPs.
Dynamic
light
scattering
(DLS),
zeta
potential
analysis,
transmission
electron
microscopy
(TEM),
Fourier
transform
infrared
(FT‐IR)
spectroscopy,
UV‐Vis
X‐ray
diffraction
(XRD)
methods
characterize
The
effect
was
estimated
in
vitro
methods,
including
reducing
power
(RP),
ferric
reducing/antioxidant
(FRAP),
2,2‐diphenyl‐1‐picrylhydrazyl
(DPPH).
To
activity
NPs,
we
carrageenan
method.
our
experiment,
administered
orally
mice
2
h
before
injection.
subsequent
inhibition
inflammation
reduction
paw
thickness
quantified.
their
effect,
malondialdehyde
(MDA),
total
capacity
(TAC)
levels
measured.
Levels
pro‐inflammatory
cytokines,
interleukin‐6
(IL‐6)
tumor
necrosis
factor‐
α
(TNF‐
),
also
results
indicate
that
have
effects.
most
promising
observed
groups
received
Beyond
their
significant
contribution
to
the
dietary
and
industrial
supplies,
marine
algae
are
considered
be
a
potential
source
of
some
unique
metabolites
with
diverse
health
benefits.
The
pharmacological
properties,
such
as
antioxidant,
anti-inflammatory,
cholesterol
homeostasis,
protein
clearance
anti-amyloidogenic
potentials
algal
endorse
protective
efficacy
against
oxidative
stress,
neuroinflammation,
mitochondrial
dysfunction,
impaired
proteostasis
which
known
implicated
in
pathophysiology
neurodegenerative
disorders
associated
complications
after
cerebral
ischemia
brain
injuries.
As
was
evident
various
preclinical
studies,
compounds
conferred
neuroprotection
wide
range
neurotoxic
stressors,
oxygen/glucose
deprivation,
hydrogen
peroxide,
glutamate,
amyloid
β,
or
1-methyl-4-phenylpyridinium
(MPP+)
and,
therefore,
hold
therapeutic
promise
for
disorders.
While
number
promising
neuroprotective
capacity
have
been
identified
over
last
decades,
few
them
had
access
clinical
trials.
However,
recent
approval
an
oligosaccharide,
sodium
oligomannate,
treatment
Alzheimer's
disease
enlightened
future
algae-based
drug
discovery.
In
this
review,
we
briefly
outline
diseases
injuries
identifying
targets
intervention,
then
review
literature
on
along
underlying
mechanism,
present
appraisal
advances.
We
also
propose
rational
strategy
facilitate
metabolites-based
development.
Marine Drugs,
Journal Year:
2020,
Volume and Issue:
18(12), P. 613 - 613
Published: Dec. 2, 2020
The
review
is
devoted
to
the
chemical
diversity
of
steroids
produced
by
soft
corals
and
their
determined
potential
activities.
There
are
about
200
that
belong
different
types
such
as
secosteroids,
spirosteroids,
epoxy-
peroxy-steroids,
steroid
glycosides,
halogenated
steroids,
polyoxygenated
containing
sulfur
or
nitrogen
heteroatoms.
Of
greatest
interest
pharmacological
activity
these
steroids.
More
than
40
exhibit
antitumor
related
with
a
confidence
level
over
90
percent.
A
group
32
shows
anti-hypercholesterolemic
percent
confidence.
Ten
anti-inflammatory
20
can
be
classified
respiratory
analeptic
drugs.
Several
rather
rare
very
specific
Steroids
anti-osteoporotic
properties
used
treat
osteoporosis,
well
have
strong
anti-eczemic
anti-psoriatic
antispasmodic
properties.
Thus,
this
probably
first
exclusive
present
known
activities
marine
Biological Trace Element Research,
Journal Year:
2022,
Volume and Issue:
201(4), P. 2071 - 2087
Published: June 4, 2022
Abstract
The
anti-inflammatory,
anti-arthritic,
and
antimicrobial
activities
of
some
common
Egyptian
seaweeds
in
addition
to
their
phytochemical
heavy
metal
contents
were
investigated.
Phytochemical
screening
the
seaweed
extracts
showed
presence
different
primary
secondary
metabolites
with
concentrations
according
species
used
solvent.
ethanolic
extract
Colpmenia
sinuosa
(CSBE2)
exhibited
maximum
anti-inflammatory
anti-arthritic
activity
at
1000
μg/ml
concentration
compared
other
extracts.
dichloromethane
Corallina
officinalis
(CORM)
exerted
highest
an
average
inhibition
zone
diameter
(AV)
=
15.29
mm
index
(AI)
1.53
antagonistic
against
Escherichia
coli
(28
mm).
It
is
followed
by
Ulva
linza
(ULGE2)
which
recorded
14.71
1.30
antifungal
Candida
albicans
(30
collected
would
therefore
be
a
very
promising
source
for
treating
inflammatory,
arthritic,
microbial
diseases.
Moreover,
investigated
variable
metals
among
various
species.
mean
took
following
order:
Fe
>
Zn
Mn
Ba
Cu
As
Cr
Ni
Pb
V
Cd
Se
Co
Mo.
Based
on
permissible
limits
set
WHO
CEVA,
studied
found
within
limits,
whereas
borderline.
Significant
correlations
observed
between
parameters.
estimated
daily
intakes
most
lower
than
recommended
intakes.
Journal of Marine Science and Engineering,
Journal Year:
2022,
Volume and Issue:
10(9), P. 1184 - 1184
Published: Aug. 24, 2022
Macroalgae
are
invaluable
constituents
of
marine
forest
environments
and
important
sources
material
for
human
needs.
However,
they
currently
at
risk
severe
decline
due
to
global
warming
negative
anthropogenic
factors.
Restoration
efforts
focus
on
beds
where
macroalgae
previously
existed,
as
well
the
creation
new
forests.
Some
artificial
seaweed
reefs
(ASRs)
have
succeeded
but
others
failed;
contributions
ASRs
formation
been
not
fully
determined.
Here,
we
review
ASRs,
benefits
macroalgal
forests,
threats
macroalgae,
restoration,
explore
current
status
ASRs.
The
published
literature
indicates
that
played
critical
roles
in
formation;
notably,
support
establishment
submerged
aquatic
vegetation
allow
ocean
afforestation.
evolved
terms
complexity
materials
used;
can
sustainably
mitigate
deforestation.
continuous
reviews
ASR
performance
essential,
improvements
always
possible.
Marine Drugs,
Journal Year:
2023,
Volume and Issue:
21(10), P. 524 - 524
Published: Sept. 30, 2023
Inflammation
is
a
defense
mechanism
of
the
body
in
response
to
harmful
stimuli
such
as
pathogens,
damaged
cells,
toxic
compounds
or
radiation.
However,
chronic
inflammation
plays
an
important
role
pathogenesis
variety
diseases.
Multiple
anti-inflammatory
drugs
are
currently
available
for
treatment
inflammation,
but
all
exhibit
less
efficacy.
This
drives
search
new
focusing
on
natural
resources.
Marine
organisms
produce
broad
spectrum
bioactive
with
activities.
Several
considered
lead
development
into
drugs.
Anti-inflammatory
have
been
extracted
from
algae,
corals,
seaweeds
and
other
marine
organisms.
We
previously
reviewed
compounds,
well
crude
extracts
isolated
echinoderms
sea
cucumbers,
urchins
starfish.
In
present
review,
we
evaluate
effects
organisms,
including
macroalgae
(seaweeds),
angiosperms
(seagrasses),
medusozoa
(jellyfish),
bryozoans
(moss
animals),
mollusks
(shellfish)
peanut
worms.
also
review
molecular
mechanisms
activity
these
compounds.
Our
objective
this
provide
overview
current
state
research
sources
prospects
their
translation
novel
Food Science & Nutrition,
Journal Year:
2021,
Volume and Issue:
9(10), P. 5755 - 5764
Published: Aug. 28, 2021
Abstract
The
traditional
use
of
Onosma
L.
species
as
a
remedy
motivated
scientists
to
discover
great
biological/pharmacological
potentials
in
this
plant.
In
the
current
study,
addition
phytochemical
composition
methanol
(MeOH),
water,
and
ethyl
acetate
extract
aerial
parts
mutabilis
Boiss.,
an
endemic
plant
flora
Kurdistan,
Iraq,
vitro
antioxidant,
cytotoxicity,
oral
toxicity
activity
were
investigated.
Results
total
phenolic
flavonoid
tests
show
MeOH
superiority,
results
Gas
chromatography–mass
spectrophotometer(GS/GS‐MS)
18
chemical
compounds
extract,
majority
detected
alkaloids
(78.77%)
steroids
(11.48%),
namely
5,8‐dihydroxy‐2‐(4‐methylpent‐3‐enyl)
naphthalene‐1,4‐dione
(48.60%),
3‐O‐Methyl‐d‐glucose
(27.49%),
β‐Sitosterol
(6.81%),
Phenol,
2,4‐bis
(1,1‐dimethyl
ethyl)‐,
phosphite
(3.46%),
24,25‐Dihydroxycholecalciferol
(3.14%).
antioxidant
superiority
phosphomolybdenum
assay,
radical
scavenging
[on
1,1‐diphenyl‐2‐picrylhydrazyl
(DPPH)
2,2′‐azino‐bis
(3‐ethylbenzothiazoline‐6‐sulfonic
acid)
(ABTS)]
assays,
reducing
power
[cupric
capacity
(CUPRAC)
ferric
(FRAP)]
assays
(1.45,
3.54,
2.33,
1.12,
1.62,
mg/ml,
respectively).
cytotoxicity
are
presented
IC
50
(inhibitory
concentration
at
50%)
on
prostate
cancer
cells
(DU‐145),
mammary
(MCF‐7),
human
cervix
carcinoma
(Hep2c),
which
values
ranged
from
28.79
41.83
μg/ml.
acute
dose‐dependent
trail
(100,
200,
300,
600
mg/kg
MeOH)
absence
behavior
appearance
changes
female
Wister
rats.
Overall,
O.
exhibited
significant
natural
probably
because
its
polar
phytochemicals,
could
be
alternative
source
for
remedial,
nutrient,
cosmetic
manufacture.
